Tsen2 - tRNA splicing endonuclease subunit 2 Gene

Mus musculus

Gene ID: 381802 | Gene type: protein coding

About Tsen2

Summary

Predicted to enable tRNA-intron Endonuclease activity. Predicted to be involved in tRNA-type intron splice site recognition and cleavage. Predicted to act upstream of or within mRNA processing and tRNA processing. Predicted to be located in centrosome; cytosol; and nucleoplasm. Predicted to be part of tRNA-intron Endonuclease complex. Human ortholog(s) of this gene implicated in pontocerebellar hypoplasia type 2B. Orthologous to human TSEN2 (tRNA splicing Endonuclease subunit 2). [provided by Alliance of Genome Resources, Apr 2022]

Tsen2 Products(4)

mRNA	Protein	Name
NM_001411784.1	NP_001398713.1	tRNA-splicing endonuclease subunit Sen2 isoform 2
NM_001411785.1	NP_001398714.1	tRNA-splicing endonuclease subunit Sen2 isoform 3
NM_001411786.1	NP_001398715.1	tRNA-splicing endonuclease subunit Sen2 isoform 4
NM_199033.3	NP_950198.1	tRNA-splicing endonuclease subunit Sen2 isoform 1

Protein Preferred Names

Protein Names

tRNA-splicing endonuclease subunit Sen2

tRNA splicing endonuclease 2 homolog

tRNA-intron endonuclease Sen2

Related Agents

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS15138	TSEN2 Human Pre-designed siRNA Set A	Pre-designed Set	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Homo sapiens	Tsen2	NCBI	NCBI:80746

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