2. Gene
  3. Alg8 - asparagine-linked glycosylation 8 (alpha-1,3-glucosyltransferase) Gene

Alg8 - asparagine-linked glycosylation 8 (alpha-1,3-glucosyltransferase) Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Mus musculus

Also known as Gm1089

Gene ID: 381903 | Gene type: protein coding

About Alg8

Summary

Predicted to enable alpha-1,3-mannosyltransferase activity and dolichyl pyrophosphate Glc1Man9GlcNAc2 alpha-1,3-glucosyltransferase activity. Involved in protein N-linked glycosylation via asparagine. Predicted to be located in endoplasmic reticulum and membrane. Predicted to be integral component of membrane. Predicted to be active in endoplasmic reticulum membrane. Is expressed in several structures, including alimentary system; midbrain; respiratory system; telencephalon; and urinary system. Human ortholog(s) of this gene implicated in congenital disorder of glycosylation Ih and polycystic liver disease. Orthologous to human ALG8 (ALG8 alpha-1,3-glucosyltransferase). [provided by Alliance of Genome Resources, Apr 2022]

Alg8 Products(1)

mRNA Protein Name
NM_199035.2 NP_950200.2 probable dolichyl pyrophosphate Glc1Man9GlcNAc2 alpha-1,3-glucosyltransferase precursor
Gene Ontology
  • Biological Process
Biological Process GO Annotation Evidence Reference Source
involved in protein N-linked glycosylation via asparagine IMP
IMP: Inferred from mutant phenotype
28375157 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

probable dolichyl pyrophosphate Glc1Man9GlcNAc2 alpha-1,3-glucosyltransferase

asparagine-linked glycosylation 8 homolog (yeast, alpha-1,3-glucosyltransferase)

asparagine-linked glycosylation protein 8 homolog

dol-P-Glc:Glc(1)Man(9)GlcNAc(2)-PP-dolichyl alpha-1,3-glucosyltransferase

dolichyl pyrophosphate Glc1Man9GlcNAc2 alpha-1,

Related Agents

Pre-clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS00596 ALG8 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Alg8 NCBI NCBI:79053