Gatc - glutamyl-tRNA(Gln) amidotransferase, subunit C Gene

Also Known as 2010003O18Rik

Species: Mus musculus

Gene Type: protein coding
Gene ID: 384281

Summary

Predicted to enable glutaminyl-tRNA synthase (glutamine-hydrolyzing) activity. Predicted to be involved in glutaminyl-tRNAGln biosynthesis via transamidation and mitochondrial translation. Predicted to act upstream of or within translation. Located in mitochondrion. Human ortholog(s) of this gene implicated in combined Oxidative Phosphorylation deficiency 42. Orthologous to human GATC (glutamyl-tRNA amidotransferase subunit C). [provided by Alliance of Genome Resources, Apr 2022]

Gatc Products (1)

mRNA Protein Name
NM_029645.3 NP_083921.1 glutamyl-tRNA(Gln) amidotransferase subunit C, mitochondrial

Gene Ontology

  • Cellular Component
Cellular Component GO Annotation Evidence References Source
located in mitochondrion IDA
IDA: Inferred from direct assay
24579914 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

glutamyl-tRNA(Gln) amidotransferase subunit C, mitochondrial

  • gatC-like protein

  • glu-AdT subunit C

  • glutamyl-tRNA(Gln) amidotransferase, subunit C homolog

Related Agents

  • Clinical Phase
  • Pre-clinical Phase

Clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Phase
HY-148511 Vidutolimod 93.85% Phase 3

Pre-clinical Phase

Bioactive Molecules (2)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-150741 ODN 2216 98.57% Unkown
HY-RS05299 GATC Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Gatc NCBI NCBI:283459