Nova2 - NOVA alternative splicing regulator 2 Gene

Mus musculus

Also known as Gm1424

Gene ID: 384569 | Gene type: protein coding

About Nova2

Summary

Enables mRNA binding activity. Involved in several processes, including negative regulation of cold-induced thermogenesis; regulation of alternative mRNA splicing, via spliceosome; and regulation of axon guidance. Acts upstream of or within regulation of RNA metabolic process. Is expressed in several structures, including central nervous system; lung; peripheral nervous system ganglion; retina; and trigeminal nerve. Orthologous to human NOVA2 (NOVA alternative splicing regulator 2). [provided by Alliance of Genome Resources, Apr 2022]

Nova2 Products(1)

mRNA	Protein	Name
NM_001029877.3	NP_001025048.2	RNA-binding protein Nova-2

Gene Ontology

Molecular Function
Biological Process

Molecular Function GO Annotation	Evidence	Reference	Source
enables RNA binding	IDA IDA: Inferred from direct assay	9789075	MGI
enables mRNA binding	IDA IDA: Inferred from direct assay	14615540	MGI
enables protein binding	IPI IPI: Inferred from physical interaction	10829067	MGI

Biological Process GO Annotation	Evidence	Reference	Source
involved in central nervous system neuron development	IMP IMP: Inferred from mutant phenotype	27223325	MGI
involved in negative regulation of cold-induced thermogenesis	IGI IGI: Inferred from genetic interaction	27635635	MGI
acts upstream of or within regulation of RNA metabolic process	IGI IGI: Inferred from genetic interaction	23359859	MGI
involved in regulation of alternative mRNA splicing, via spliceosome	IMP IMP: Inferred from mutant phenotype	14615540	MGI
involved in regulation of axon guidance	IMP IMP: Inferred from mutant phenotype	27223325	MGI

EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

Protein Preferred Names

Protein Names

RNA-binding protein Nova-2

neuro-oncological ventral antigen 2

Related Agents

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS09456	NOVA2 Human Pre-designed siRNA Set A	Pre-designed Set	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Homo sapiens	Nova2	NCBI	NCBI:4858

Name
Email *

	Sorry, but the email address you supplied was invalid.