Nova2 - NOVA alternative splicing regulator 2 Gene

Also Known as Gm1424

Species: Mus musculus

Gene Type: protein coding
Gene ID: 384569

Summary

Enables mRNA binding activity. Involved in several processes, including negative regulation of cold-induced thermogenesis; regulation of alternative mRNA splicing, via spliceosome; and regulation of axon guidance. Acts upstream of or within regulation of RNA metabolic process. Is expressed in several structures, including central nervous system; lung; peripheral nervous system ganglion; retina; and trigeminal nerve. Orthologous to human NOVA2 (NOVA alternative splicing regulator 2). [provided by Alliance of Genome Resources, Apr 2022]

Nova2 Products (1)

mRNA Protein Name
NM_001029877.3 NP_001025048.2 RNA-binding protein Nova-2

Gene Ontology

  • Molecular Function
  • Biological Process
Molecular Function GO Annotation Evidence References Source
enables RNA binding IDA
IDA: Inferred from direct assay
9789075 MGI
enables mRNA binding IDA
IDA: Inferred from direct assay
14615540 MGI
enables protein binding IPI
IPI: Inferred from physical interaction
10829067 MGI
Biological Process GO Annotation Evidence References Source
involved in central nervous system neuron development IMP
IMP: Inferred from mutant phenotype
27223325 MGI
involved in negative regulation of cold-induced thermogenesis IGI
IGI: Inferred from genetic interaction
27635635 MGI
acts upstream of or within regulation of RNA metabolic process IGI
IGI: Inferred from genetic interaction
23359859 MGI
involved in regulation of alternative mRNA splicing, via spliceosome IMP
IMP: Inferred from mutant phenotype
14615540 MGI
involved in regulation of axon guidance IMP
IMP: Inferred from mutant phenotype
27223325 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

RNA-binding protein Nova-2

  • neuro-oncological ventral antigen 2

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS09456 NOVA2 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Nova2 NCBI NCBI:4858