2. Gene
  3. Nsfl1c - NSFL1 (p97) cofactor (p47) Gene

Nsfl1c - NSFL1 (p97) cofactor (p47) Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Mus musculus

Also known as p47; Stxbp3a; Munc-18c

Gene ID: 386649 | Gene type: protein coding

About Nsfl1c

Summary

Predicted to enable ATPase binding activity and ubiquitin binding activity. Predicted to contribute to phospholipid binding activity. Predicted to be involved in several processes, including establishment of mitotic spindle orientation; negative regulation of protein localization to centrosome; and positive regulation of mitotic centrosome separation. Predicted to be located in cytoskeleton; nucleoplasm; and plasma membrane. Predicted to be part of VCP-NSFL1C complex. Predicted to be active in cytosol and nucleus. Is expressed in central nervous system and retina. Orthologous to human NSFL1C (NSFL1 cofactor). [provided by Alliance of Genome Resources, Apr 2022]

Nsfl1c Products(2)

mRNA Protein Name
NM_001291074.1 NP_001278003.1 NSFL1 cofactor p47 isoform b
NM_198326.3 NP_938085.1 NSFL1 cofactor p47 isoform a
Gene Ontology
  • Molecular Function
  • Cellular Component
Molecular Function GO Annotation Evidence Reference Source
enables protein binding IPI
IPI: Inferred from physical interaction
14988733 MGI
Cellular Component GO Annotation Evidence Reference Source
part of VCP-NSFL1C complex IPI
IPI: Inferred from physical interaction
14988733 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

NSFL1 cofactor p47

p97 cofactor p47

Related Agents

Pre-clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS09592 NSFL1C Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Nsfl1c NCBI NCBI:55968