2. Gene
  3. Mir182 - microRNA 182 Gene

Mir182 - microRNA 182 Gene

  • Gene
  • Agent
  • Ortholog
Mus musculus

Also known as Mirn182; mir-182; mmu-mir-182

Gene ID: 387177 | Gene type: ncRNA

About Mir182

Summary

MicroRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted MicroRNA stem-loop. [provided by RefSeq, Sep 2009]

Gene Ontology
  • Biological Process
Biological Process GO Annotation Evidence Reference Source
acts upstream of or within Wnt signaling pathway IDA
IDA: Inferred from direct assay
16682203 MGI
acts upstream of or within cellular response to leukemia inhibitory factor IEP
IEP: Inferred from expression pattern
20439489 MGI
acts upstream of or within cellular response to lipopolysaccharide IDA
IDA: Inferred from direct assay
21247879 MGI
acts upstream of or within female sex differentiation IEP
IEP: Inferred from expression pattern
23946534 MGI
acts upstream of or within negative effect gene expression IGI
IGI: Inferred from genetic interaction
28819115 MGI
acts upstream of or within miRNA-mediated post-transcriptional gene silencing IGI
IGI: Inferred from genetic interaction
28819115 MGI
acts upstream of or within regulation of gene expression IGI
IGI: Inferred from genetic interaction
23341629 MGI
acts upstream of or within retina development in camera-type eye IGI
IGI: Inferred from genetic interaction
23341629 MGI
acts upstream of or within retinal cone cell development IGI
IGI: Inferred from genetic interaction
23341629 MGI
acts upstream of or within sensory perception of sound IEP
IEP: Inferred from expression pattern
23646144 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

Related Agents

Pre-clinical Phase
Bioactive Molecules (16)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-R00339 hsa-miR-182-5p mimic 90.81% Unkown
HY-R02701A mmu-miR-182-5p agomir 95.86% Unkown
HY-RI00339 hsa-miR-182-5p inhibitor 94.25% Unkown
HY-R02701 mmu-miR-182-5p mimic 92.17% Unkown
HY-RI02701 mmu-miR-182-5p inhibitor 94.22% Unkown
HY-R00337 hsa-miR-182-3p mimic / Unkown
HY-R00337A hsa-miR-182-3p agomir / Unkown
HY-R00339A hsa-miR-182-5p agomir / Unkown
HY-R02700 mmu-miR-182-3p mimic / Unkown
HY-R02700A mmu-miR-182-3p agomir / Unkown
HY-RI00337 hsa-miR-182-3p inhibitor / Unkown
HY-RI00337A hsa-miR-182-3p antagomir / Unkown
HY-RI00339A hsa-miR-182-5p antagomir / Unkown
HY-RI02700 mmu-miR-182-3p inhibitor / Unkown
HY-RI02700A mmu-miR-182-3p antagomir / Unkown
HY-RI02701A mmu-miR-182-5p antagomir / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Mir182 NCBI NCBI:406958