IGFL3 - IGF like family member 3 Gene

Also Known as UNQ483

Species: Homo sapiens

Gene Type: protein coding
Gene ID: 388555

About IGFL3

Cytogenetic location: 19q13.32 Genomic coordinates (GRCh38): 19:46,120,067-46,124,688 (from NCBI)

This gene has 1 transcript (splice variant), 30 orthologues and 3 paralogues. Low expression observed in reference dataset.

Summary

IGFL3 belongs to the insulin-like growth factor (IGF; see MIM 147440) family of signaling molecules that play critical roles in cellular energy metabolism and in growth and development, especially prenatal growth (Emtage et al., 2006 [PubMed 16890402]).[supplied by OMIM, Mar 2008]

IGFL3 Products (1)

mRNA Protein Name
NM_207393.2 NP_997276.1 insulin growth factor-like family member 3 precursor

Gene Ontology

  • Molecular Function
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables signaling receptor binding IPI
IPI: Inferred from physical interaction
21454693 GOA
Cellular Component GO Annotation Evidence References Source
located in extracellular space IDA
IDA: Inferred from direct assay
21454693 GOA
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

IGFL3 Protein Structure

IGFL

IGFL: Insulin growth factor-like family (26 - 115)

  • 0
  • 100
  • 125 a.a.
Protein Preferred Names Protein Names

insulin growth factor-like family member 3

  • RPRC483

Related Diseases

Diseases Alias
Testicular Disease

  • Testicular Dysfunction

  • Testicular Diseases

  • Disorder Of Testis

  • Testis Disorder

  • Testicular Disorders
Cryptorchidism, Unilateral Or Bilateral

  • Cryptorchidism

  • Undescended Testicle

  • Undescended Testis

  • Cryptorchism

  • Undescended Testicles

  • CRYPTO

  • Impaired Testicular Descent

  • Cryptosporidiosis

  • Retained Testis

  • Unilateral Cryptorchidism

  • Unilateral Undescended Testis

  • Nondescent Unilateral Testicle

  • Unilateral Cryptorchism

  • Ectopic Testis, Unilateral

  • Bilateral Cryptorchidism

  • Bilateral Cryptorchism

  • Bilateral Nondescent Testicle

  • Bilateral Undescended Testes

  • Bilateral Ectopic Testes
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS06634 IGFL3 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Mus musculus IGFL3 MGD MGI:2685426
Rattus norvegicus IGFL3 RGD RGD:2324129
Others IGFL3 NCBI