FRRS1 - ferric chelate reductase 1 Gene

Also Known as SDR2; SDFR2

Species: Homo sapiens

Gene Type: protein coding
Gene ID: 391059

About FRRS1

Cytogenetic location: 1p21.2 Genomic coordinates (GRCh38): 1:99,703,970-99,766,635 (from NCBI)

This gene has 5 transcripts (splice variants), 224 orthologues and 2 paralogues. Broad expression in liver (RPKM 6.9), placenta (RPKM 5.3) and 22 other tissues.

Summary

Members of the cytochrome b561 (CYB561; MIM 600019) family, including FRRS1, reduce ferric to ferrous iron before its transport from the endosome to the cytoplasm (Vargas et al., 2003 [PubMed 14499595]).[supplied by OMIM, Mar 2008]

FRRS1 Products (2)

mRNA Protein Name
NM_001013660.4 NP_001013682.2 ferric-chelate reductase 1 isoform 1 precursor
NM_001361041.2 NP_001347970.1 ferric-chelate reductase 1 isoform 2 precursor

FRRS1 Protein Structure

Reeler

Reeler: Reeler domain (31 - 156)

DOMON

DOMON: DOMON domain (217 - 331)

  • 0
  • 100
  • 200
  • 300
  • 400
  • 500
  • 626 a.a.
Protein Preferred Names Protein Names

ferric-chelate reductase 1

  • SDR-2

Related Diseases

Diseases Alias
Lice Infestation

  • Pediculosis

  • Louse Infestation

  • Mixed Pediculosis

  • Lice Infestations

  • Infestation By Pediculus

  • Mixed Pediculosis Infestation

  • Pediculosis + Lice

  • Pediculosis And Phthirus Infection

  • Pediculosis And Phthirus Infections

  • Pediculosis And Phthirus Infestation

  • Infestation By Anoplura

  • Pediculus Infestation

  • Lice Nos
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (2)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS05110 FRRS1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS05111 FRRS1L Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Felis catus FRRS1 VGNC VGNC:62367
Canis familiaris FRRS1 VGNC VGNC:40985
Rattus norvegicus FRRS1 RGD RGD:1306883
Macaca mulatta FRRS1 VGNC VGNC:72795
Mus musculus FRRS1 MGD MGI:108076
Others FRRS1 NCBI