ACVR2A - activin A receptor type 2A Gene

Sus scrofa

Also known as ACVR2

Gene ID: 397282 | Gene type: protein coding

About ACVR2A

Primary_assembly 15: 4,173,805-4,259,706 reverse strand.Sscrofa11.1:CM000826.5

This gene has 1 transcript (splice variant), 275 orthologues and 11 paralogues. Ubiquitous expression in subcutaneous adipose (RPKM 5.8), heart (RPKM 5.6) and 8 other tissues.

ACVR2A Products(1)

mRNA	Protein	Name
NM_001204765.1	NP_001191694.1	activin receptor type-2A precursor

ACVR2A Protein Structure

Activin_recp

STKc_ACVR2a

0
100
200
300
400
513 a.a.

Protein Preferred Names

Protein Names

activin receptor type-2A

activin receptor IIA

Related Agents

Approval

Inhibitory Antibodies (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-P99590	Sotatercept		99.94%	Unkown

Clinical Phase

Bioactive Molecules (2)

Cat. No.	Product Name	Effect	Purity	Phase
HY-157442	GLPG3312	Antagonist	98.63%	Phase 1
HY-117887	Fidrisertib	Inhibitor	98.17%	Phase 1

Inhibitory Antibodies (1)

Cat. No.	Product Name	Effect	Purity	Phase
HY-P99355	Bimagrumab	Inhibitor	99.31%	Phase 3

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-185430	HM-279	Inhibitor	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Homo sapiens	ACVR2A	NCBI	NCBI:92
Macaca fascicularis	ACVR2A	NCBI	NCBI:102121129
Mus musculus	ACVR2A	NCBI	NCBI:11480
Rattus norvegicus	ACVR2A	NCBI	NCBI:29263

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