RGPD1 - RANBP2 like and GRIP domain containing 1 Gene

Also Known as RGP1; RGPD2; RanBP2L2; ranBP2L6

Species: Homo sapiens

Gene Type: protein coding
Gene ID: 400966

About RGPD1

Cytogenetic location: 2p11.2 Genomic coordinates (GRCh38): 2:86,913,324-87,013,976 (from NCBI)

This gene has 4 transcripts (splice variants), 21 orthologues and 10 paralogues. Broad expression in testis (RPKM 17.9), liver (RPKM 7.1) and 23 other tissues.

Summary

Predicted to contribute to GTPase activator activity. Predicted to be involved in NLS-bearing protein import into nucleus. Predicted to be part of nuclear pore. Predicted to be active in cytoplasm. [provided by Alliance of Genome Resources, Apr 2022]

RGPD1 Products (3)

mRNA Protein Name
NM_001024457.4 NP_001019628.3 RANBP2-like and GRIP domain-containing protein 1 isoform 2
NM_001382344.1 NP_001369273.1 RANBP2-like and GRIP domain-containing protein 1 isoform 1
NM_001410915.1 NP_001397844.1 RANBP2-like and GRIP domain-containing protein 1 isoform 3

RGPD1 Protein Structure

TPR_1

TPR_1: Tetratricopeptide repeat (52 - 82)

Ran_BP1

Ran_BP1: RanBP1 domain (1033 - 1153)

Ran_BP1

Ran_BP1: RanBP1 domain (1330 - 1450)

GRIP

GRIP: GRIP domain (1689 - 1732)

  • 0
  • 300
  • 600
  • 900
  • 1200
  • 1500
  • 1748 a.a.
Protein Preferred Names Protein Names

RANBP2-like and GRIP domain-containing protein 1

  • RANBP2-like and GRIP domain-containing protein 1/2

Related Diseases

Diseases Alias
Myoclonic Cerebellar Dyssynergia

  • Dyssynergia Cerebellaris Myoclonica

  • Progressive Cerebellar Tremor

  • Dentate Cerebellar Ataxia

  • Dentatorubral Atrophy

  • Dyssynergia Cerebellaris Progressiva

  • Myoclonus And Ataxia

  • Primary Dentatum Atrophy

  • Progressive Myoclonus Ataxia

  • Ramsay Hunt Cerebellar Syndrome

  • Ramsay Hunt Syndrome Type 1
Charcot-Marie-Tooth Disease, Axonal, Type 2dd

  • CMT2DD

  • Charcot-Marie-Tooth Neuropathy, Type 2dd

  • Charcot-Marie-Tooth Disease Type 2dd

  • Atp1a1-Related Autosomal Dominant Charcot-Marie-Tooth Disease Type 2

  • Atp1a1-Related Cmt2

  • Autosomal Dominant Charcot-Marie-Tooth Disease Type 2dd

  • Charcot-Marie-Tooth Disease 2dd
Cerebrooculofacioskeletal Syndrome

  • Cerebro-Oculo-Facio-Skeletal Syndrome

  • Cofs Syndrome

  • Pena-Shokeir Syndrome Type 2

  • Pena Shokeir Syndrome Type 2
Retinitis Pigmentosa

  • RP

  • Rod-Cone Dystrophy

  • Autosomal Recessive Retinitis Pigmentosa

  • Non-Syndromic Retinitis Pigmentosa

  • Pericentral Pigmentary Retinopathy

  • Pigmentary Retinopathy

  • Tapetoretinal Degeneration

  • Rcd

  • Retinitis Pigmentosa Autosomal Recessive

  • ARRP

  • Retinitis Pigmentosa, Autosomal Recessive

  • Retinitis Pigmentosa 1
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS11898 RGPD1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Mus musculus RGPD1 MGD MGI:894323