XKRX - XK related X-linked Gene

Homo sapiens

Also known as XKR2; XRG2; XPLAC

Gene ID: 402415 | Gene type: protein coding

About XKRX

Cytogenetic location: Xq22.1 Genomic coordinates (GRCh38): X:100,886,916-100,959,343 (from NCBI)

This gene has 2 transcripts (splice variants), 203 orthologues and 2 paralogues. Broad expression in skin (RPKM 2.6), lymph node (RPKM 0.8) and 19 other tissues.

Summary

This gene encodes a protein that is related to a component of the XK/Kell complex of the Kell blood group system. The encoded protein includes several transmembrane domains, is known to be exposed to the cell surface, and may function as a membrane transporter. [provided by RefSeq, May 2010]

XKRX Products(1)

mRNA	Protein	Name
NM_212559.3	NP_997724.2	XK-related protein 2

XKRX Protein Structure

XK-related

0
100
200
300
400
449 a.a.

Protein Preferred Names

Protein Names

XK-related protein 2

X Kell blood group precursor-related, X-linked

Related Diseases

Diseases

Alias

Mcleod Syndrome

Mcleod Neuroacanthocytosis Syndrome	MLS
X-Linked Mcleod Syndrome	Mcleod Phenotype
Neuroacanthocytosis, Mcleod Type	Mcleod Syndrome With Or Without Chronic Granulomatous Disease
MCLDS	Mcleod Type Neuroacanthocytosis
Mcleod Syndrome With Chronic Granulomatous Disease	Neuroacanthocytosis Mcleod Type
Blood Group Deletion Syndrome

Neuroacanthocytosis

Neuroacanthocytosis Syndrome

Choreoacanthocytosis

Chorea-Acanthocytosis	CHAC
Acanthocytosis With Neurologic Disorder	Levine-Critchley Syndrome
Choreaacanthocytosis	Chorea Acanthocytosis
Neuroacanthocytosis	Levine-Critchley Syndrome, Formerly
Neuroacanthocytosis, Formerly	Choreo-Acanthocytosis
Acanthocytosis Chorea	Chorea Acanthocytosis Syndrome

Diseases	Alias
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS15883	XKRX Human Pre-designed siRNA Set A		/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Mus musculus	XKRX	MGD	MGI:3584011
Bos taurus	XKRX	VGNC	VGNC:56961
Rattus norvegicus	XKRX	RGD	RGD:1359223