Opa3 - optic atrophy 3 Gene

Also Known as Gm472; Gm1425; D630048P19Rik

Species: Mus musculus

Gene Type: protein coding
Gene ID: 403187

Summary

Acts upstream of or within several processes, including fat cell differentiation; mitochondrion morphogenesis; and neuromuscular process. Located in mitochondrion. Is expressed in several structures, including eye; jaw; musculoskeletal system; optic nerve; and salivary gland. Used to study 3-methylglutaconic aciduria type 3. Human ortholog(s) of this gene implicated in 3-methylglutaconic aciduria type 3 and optic atrophy 3. Orthologous to human OPA3 (outer mitochondrial membrane lipid metabolism regulator OPA3). [provided by Alliance of Genome Resources, Apr 2022]

Opa3 Products (1)

mRNA Protein Name
NM_207525.3 NP_997408.2 optic atrophy 3 protein homolog

Gene Ontology

  • Biological Process
  • Cellular Component
Biological Process GO Annotation Evidence References Source
acts upstream of or within bone development IMP
IMP: Inferred from mutant phenotype
27106103 MGI
acts upstream of or within fat cell differentiation IMP
IMP: Inferred from mutant phenotype
27106103 MGI
acts upstream of or within mitochondrion organization IMP
IMP: Inferred from mutant phenotype
21613372 MGI
acts upstream of or within neuromuscular process IMP
IMP: Inferred from mutant phenotype
18222992 MGI
acts upstream of or within regulation of growth IMP
IMP: Inferred from mutant phenotype
18222992 MGI
acts upstream of or within regulation of lipid metabolic process IMP
IMP: Inferred from mutant phenotype
22869679 MGI
Cellular Component GO Annotation Evidence References Source
located in mitochondrion IDA
IDA: Inferred from direct assay
21613372 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

optic atrophy 3 protein homolog

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS09790 OPA3 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Opa3 NCBI NCBI:80207