2. Gene
  3. Iqsec3 - IQ motif and Sec7 domain ArfGEF 3 Gene

Iqsec3 - IQ motif and Sec7 domain ArfGEF 3 Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Rattus norvegicus

Also known as sag

Gene ID: 404781 | Gene type: protein coding

About Iqsec3

Summary

Predicted to enable guanyl-nucleotide exchange factor activity. Involved in activation of GTPase activity; regulation of small GTPase mediated signal transduction; and synapse organization. Is active in GABA-ergic synapse. Orthologous to human IQSEC3 (IQ motif and Sec7 domain ArfGEF 3). [provided by Alliance of Genome Resources, Apr 2022]

Iqsec3 Products(1)

mRNA Protein Name
NM_207617.1 NP_997500.1 IQ motif and SEC7 domain-containing protein 3
Gene Ontology
  • Biological Process
  • Cellular Component
Biological Process GO Annotation Evidence Reference Source
involved in activation of GTPase activity IDA
IDA: Inferred from direct assay
21198641 RGD
involved in postsynapse organization IDA
IDA: Inferred from direct assay
27002143 RGD
involved in postsynapse organization IMP
IMP: Inferred from mutant phenotype
27002143 RGD
involved in regulation of small GTPase mediated signal transduction IDA
IDA: Inferred from direct assay
21198641 RGD
Cellular Component GO Annotation Evidence Reference Source
is active in GABA-ergic synapse IDA
IDA: Inferred from direct assay
27002143 RGD
is active in GABA-ergic synapse IMP
IMP: Inferred from mutant phenotype
27002143 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

IQ motif and SEC7 domain-containing protein 3

IQ motif and Sec7 domain 3

potential synaptic guanine nucleotide exchange factor for Arf

synArfGEF

synArfGEF-Po

Related Agents

Pre-clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS06890 IQSEC3 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Iqsec3 NCBI NCBI:440073