MIR211 - microRNA 211 Gene

Homo sapiens

Also known as MIRN211; mir-211

Gene ID: 406993 | Gene type: ncRNA

About MIR211

Cytogenetic location: 15q13.3 Genomic coordinates (GRCh38): 15:31,065,032-31,065,141 (from NCBI)

This gene has 1 transcript (splice variant), 63 orthologues and 1 paralogue.

Summary

MicroRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted MicroRNA stem-loop. [provided by RefSeq, Sep 2009]

Gene Ontology

Molecular Function
Biological Process

Molecular Function GO Annotation	Evidence	Reference	Source
enables mRNA base-pairing translational repressor activity	IDA IDA: Inferred from direct assay	21109473	GOA

Biological Process GO Annotation	Evidence	Reference	Source
involved in miRNA-mediated gene silencing by mRNA destabilization	IDA IDA: Inferred from direct assay	21109473	GOA

EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

Related Diseases

Diseases

Alias

Melanoma

Malignant Melanoma	Cutaneous Melanoma
Naevocarcinoma	Malignant Melanomas

Intestinal Atresia

Stomach Disease

Gastropathy	Stomach Diseases
Gastric Disease	Stomach Disorder
Gastric Disorder	Stomach Disorders

Oral Cavity Cancer

Malignant Neoplasm Of Floor Of Mouth	Oral Cavity Carcinoma
Malignant Neoplasm Of Mouth

Chromosome 15q13.3 Deletion Syndrome

Chromosome 15q13.3 Microdeletion Syndrome	15q13.3 Microdeletion Syndrome
15q13.3 Microdeletion	Microdeletion 15q13.3 Syndrome
Del(15)(Q13.3)	Monosomy 15q13.3

Gallbladder Disease

Gallbladder Diseases	Gall Bladder
Gall Bladder Diseases	Abnormal Gallbladder Function

Large Intestine Cancer

Renal Cell Carcinoma, Nonpapillary

Renal Cell Carcinoma	RCC
Nonpapillary Renal Cell Carcinoma	Clear Cell Renal Cell Carcinoma
Hypernephroma	Adenocarcinoma Of Kidney
Renal Carcinoma, Chromophobe, Somatic	Clear Cell Carcinoma Of Kidney
Clear-Cell Metastatic Renal Cell Carcinoma	Clear Cell Renal Carcinoma
Renal Cell Carcinoma, Somatic	Conventional Renal Cell Carcinoma
Conventional Renal Cell Carcinoma	Renal Clear Cell Carcinoma
Ccrcc	Hereditary Clear Cell Renal Cell Carcinoma
Carcinoma, Renal Cell	Renal Cell Carcinoma, Clear Cell, Somatic
Renal Cell Carcinoma, Clear Cell	Clear Cell Kidney Carcinoma
Clear Cell Rcc	Cystic-Multilocular Variant
Clear Cell Renal Cell Adenocarcinoma	Hereditary Clear Cell Renal Cell Adenocarcinoma
Common Renal Cell Carcinoma	Crcc
Renal Cell Carcinoma Non-Papillary	Carcinoma Renal Cell
Renal Cell Cancer	Carcinoma, Renal Cell, Nonpapillary

Gastrointestinal System Cancer

Digestive System Neoplasms	Gastrointestinal Neoplasms
Digestive System Cancer	Gastrointestinal Tract Cancer
Gi Tumor	Digestive System Neoplasm
Digestive System Carcinoma	Malignant Neoplasm Of Gastrointestinal Tract
Cancer Of Digestive System

Thoracic Cancer

Thoracic Tumor	Thorax Cancer
Thorax Neoplasm	Tumor Of Thorax
Thoracic Neoplasms

Colonic Disease

Colonic Diseases

Colon Disorder

Ovary Epithelial Cancer

Ovarian Surface Epithelial-Stromal Tumor

Epithelial Tumor Of Ovary

Intestinal Disease

Intestinal Diseases

Gastrointestinal System Disease

Gastrointestinal Disease	Gastrointestinal Diseases
Alimentary System Disease	Digestive System Disorder
Gastroenteropathy	Gastrointestinal Disorder
Git Disease	Digestive System Diseases
Gastrointestinal Disorders	Digestive System Disease
Digestive System Disorders

Lung Cancer

Lung Carcinoma	Non-Small Cell Lung Carcinoma
Lung Cancer, Susceptibility To	Lung Cancer, Protection Against
Adenocarcinoma Of Lung, Somatic	Adenocarcinoma Of Lung, Response To Tyrosine Kinase Inhibitor In
Nonsmall Cell Lung Cancer	Lung Neoplasm
Carcinoma Of Lung	Lung Non-Small Cell Carcinoma
Non-Small Cell Lung Cancer	Nsclc
Lung Neoplasms	Malignant Neoplasm Of Lung
Alveolar Cell Carcinoma	Nonsmall Cell Lung Cancer, Somatic
Nonsmall Cell Lung Cancer, Response To Tyrosine Kinase Inhibitor In	Nonsmall Cell Lung Cancer, Susceptibility To
Lung Cancer, Somatic	Lung Cancer, Resistance To
Cancer Of Lung	Cancer Of Bronchus
Cancer Of The Lung	Lung Malignancies
Lung Malignant Tumors	Malignant Lung Tumor
Malignant Tumor Of Lung	Pulmonary Cancer
Pulmonary Carcinoma	Pulmonary Neoplasms
Respiratory Carcinoma	LNCR
Adenocarcinoma Of Lung	Neoplasm Of Lung
Cancer Lung	Carcinoma Non-Small Cell Lung
Carcinoma, Non-Small-Cell Lung	Lung Cancers
Lung Carcinomas	Cancer, Lung
Cancer, Lung, Non-Small Cell	Primary Malignant Neoplasm Of Lung
Bronchioloalveolar Adenocarcinoma

Mature B-Cell Neoplasm

Mature B-Cell Lymphocytic Neoplasm	Neoplasm Of Mature B-Cells
Mature B-Cell Non-Hodgkin Neoplasm With Leukaemic Behaviour

Microphthalmia

Microphthalmos	Isolated Anophthalmia-Microphthalmia Syndrome
Isolated Microphthalmia-Anophthalmia-Coloboma	Simple Microphthalmos
Clinical Anophthalmia	Isolated Anophthalmia - Microphthalmia
Isolated Pure Microphthalmia	Mac Spectrum
Microphthalmia-Anophthalmia-Coloboma Spectrum	Primitive Anophthalmia
Globe Of Eye Small	Small Eyeball
Hypoplasia Of Eye	Isolated Nanophthalmos
Rudimentary Eye	Dysplasia Of Eye

Respiratory System Cancer

Gallbladder Cancer

Gallbladder Carcinoma	Gallbladder Neoplasm
Malignant Neoplasm Of Gallbladder	Malignant Tumour Of Gallbladder
Gallbladder Ca	Localized Malignant Gallbladder Neoplasm
Malignant Tumor Of The Gallbladder	Tumor Of The Gallbladder
Cancer Of The Gallbladder	Carcinoma Gallbladder
Carcinoma Of Gallbladder	Gallbladder Neoplasms
Malignant Neoplasm Of Gallbladder Localized	Cancer Of Gallbladder
Primary Malignant Neoplasm Of Gallbladder

Breast Disease

Breast Diseases

Endocrine Gland Cancer

Endocrine Neoplasm	Malignant Neoplasm Of Endocrine Gland
Endocrine Gland Neoplasms	Endocrine Tumor
Malignant Endocrine Tumor	Malignant Tumour Of Endocrine Gland
Neoplasm Of Endocrine Gland	Neoplasm Of Endocrine System
Neoplasm Of The Endocrine System	Carcinoma Of Endocrine Gland

Colorectal Cancer

Colon Cancer	Colorectal Carcinoma
Colon Carcinoma	Colorectal Cancer, Susceptibility To
Carcinoma Of Colon	CRC
Colorectal Cancer With Chromosomal Instability, Somatic	Colon Cancer, Somatic
Colon Cancer, Susceptibility To	Colonic Neoplasms
Colorectal Neoplasms	Colorectal Cancer, Somatic
Colon Cancer, Advanced, Somatic	Colonic Carcinoma
Colorectal Carcinomas	Colon Cancers
Colorectal Cancers	Cancer, Colorectal, Somatic
Cancer, Colon	Cancer, Colorectal, Susceptibility To
Colorectal Neoplasm	Colonic Neoplasm
Malignant Tumor Of Colon

Ocular Cancer

Eye Neoplasm	Eye Carcinoma
Eye Cancer	Eye Neoplasms
Malignant Eye Neoplasm	Neoplasm Of Eye
Neoplasm Of Eye Proper	Ocular Tumor
Carcinoma Of Eye	Ocular Carcinoma
Malignant Tumor Of Eye

Malignant Exocrine Pancreas Neoplasm

Malignant Neoplasm Of The Exocrine Pancreas	Malignant Tumor Of Exocrine Pancreas
Malignant Tumour Of Exocrine Pancreas

Bone Sarcoma

Bladder Disease

Bladder Diseases	Urinary Bladder Diseases
Urinary Bladder Disease

Sensory System Disease

Biliary Tract Cancer

Malignant Tumour Of Biliary Tract	Biliary Tract Neoplasms
Biliary Tract Neoplasm

Retinal Cancer

Malignant Neoplasm Of Retina	Retinal Neoplasms
Malignant Retinal Neoplasm	Malignant Tumor Of Retina
Neoplasm Of Retina	Retinal Tumor
Retinal Neoplasm	Cancer Of The Retina
Malignant Retinal Tumour	Malignant Tumour Of Retina
Primary Malignant Neoplasm Of Retina

Respiratory System Disease

Abnormality Of The Respiratory System	Respiration Disorders
Respiratory Tract Diseases

Retinal Disease

Retinal Diseases	Retinal Disorder
Retinal Disorders

Gastric Cancer

Stomach Cancer	Gastric Carcinoma
Stomach Carcinoma	Gastric Cancer, Somatic
Gastric Neoplasm	Carcinoma Of Stomach
Stomach Neoplasms	Malignant Neoplasm Of Stomach
Gastric Cancer Risk After H. Pylori Infection	Cancer Of The Stomach
Adult Stomach Cancer	Adult Stomach Carcinoma
GASC	Gastric Cancer Intestinal
Gastric Cancers	Gastric Carcinomas
Cancer, Gastric	Stomach Neoplasm
Malignant Neoplasm Of Body Of Stomach	Malignant Tumor Of Lesser Curve Of Stomach
Gastrocarcinoma Of Unspecified Site	Leather Bottle Stomach
Carcinoma Of Fundus Of Stomach	Cancer Of Fundus Of Stomach
Primary Malignant Neoplasm Of Body Of Stomach	Cancer Of Body Of Stomach
Primary Malignant Neoplasm Of Pyloric Antrum	Pyloric Antrum Cancer
Malignant Tumour Of Stomach

Esophageal Disease

Esophageal Diseases	Esophageal Ulcer
Esophageal Disorder	Ulcer Of Esophagus

Spinal Disease

Spinal Disorder

Spinal Diseases

Plasma Cell Neoplasm

Plasma Cell Dyscrasia	Paraproteinemias
Plasma Cell Tumour	Plasmacytic Tumor
Multiple Myeloma	Plasmacytoma
Plasma Cell Tumours	Plasma Cells Dyscrasia

Oral Squamous Cell Carcinoma

Mouth Squamous Cell Carcinoma

Squamous Cell Carcinoma Of Mouth

Malignant Astrocytoma

Astrocytic Tumor	Astrocytoma Of Brain
Astrocytoma Of Cerebrum	Astroglioma
Cerebral Astrocytoma	Astrocytoma

Pancreatic Ductal Adenocarcinoma

Ductal Adenocarcinoma Of The Pancreas

Eye Disease

Eye Diseases	Abnormality Of The Eye
Toxoplasma Oculopathy

Esophageal Cancer

Esophageal Carcinoma	Carcinoma Of Esophagus
Esophageal Squamous Cell Carcinoma, Somatic	Esophageal Carcinoma, Somatic
Esophagus Cancer	Gastric Cardia Adenocarcinoma
Esophageal Neoplasms	Esophageal Cancer, Somatic
Cancer Of Esophagus	Cancer Of Oesophagus
Carcinoma Of Oesophagus	Ca Lower Third Oesophagus
Ca Middle Third Oesophagus	Malignant Neoplasm Of Distal Third Of Esophagus
Malignant Neoplasm Of Lower Third Of Oesophagus	Malignant Neoplasm Of Middle Third Of Oesophagus
Malignant Neoplasm Of Proximal Third Of Esophagus	Malignant Neoplasm Of Upper Third Esophagus
Malignant Tumor Of Abdominal Esophagus	Malignant Tumor Of Distal Third Of Esophagus
Malignant Tumor Of Proximal Third Of Esophagus	Malignant Tumor Of The Middle Third Of The Esophagus
ESCR	Aerodigestive Tract Cancer
Escc	Esophageal Squamous Cell Carcinoma
Cancer, Esophageal	Malignant Neoplasm Of Esophagus
Squamous Cell Carcinoma Of Esophagus	Malignant Neoplasm Of Middle Third Of Esophagus

Connective Tissue Disease

Connective Tissue Diseases	Connective Tissue Disorder
Abnormality Of Connective Tissue	Disorder Of Connective Tissue
Connective Tissue Disorders

Nervous System Disease

Abnormality Of The Nervous System	Nervous System Diseases
Nervous System Disorder

Hirschsprung Disease 1

Hirschsprung Disease	Aganglionic Megacolon
Hscr	Hirschsprung'S Disease
Congenital Megacolon	Congenital Intestinal Aganglionosis
Colonic Aganglionosis	Hirschsprung Disease, Susceptibility To, 1
Hirschsprung Disease, Protection Against	HSCR1
Mgc	Pelvirectal Achalasia
Total Intestinal Aganglionosis	Megacolon, Aganglionic
Macrocolon	Hscr 1
Hirschsprung Disease Type 1	Hirschsprung Disease, Type 1
Congenital Dilatation Of Colon	Aganglionosis
Congenital Aganglionic Megacolon	Aganglionosis Of Colon
Bowel Aganglionosis	Colon Aganglionosis
Hirschsprung Megacolon

Lymphoma, Non-Hodgkin, Familial

Non-Hodgkin Lymphoma	Lymphoma, Non-Hodgkin
NHL	Lymphoma, Non-Hodgkin, Somatic
Lymphoma, Follicular, Somatic	Familial Non-Hodgkin Lymphoma
Lymphoma Non-Hodgkins	Follicular Lymphoma, Somatic
Lymphosarcoma	Non-Hodgkins Lymphoma

Diseases	Alias
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase

Bioactive Molecules (20)

Cat. No.	Product Name	Purity	Rare Diseases
HY-R00438	hsa-miR-211-5p mimic	95.01%	Unkown
HY-R00433	hsa-miR-211-3p mimic	/	Unkown
HY-R00433A	hsa-miR-211-3p agomir	/	Unkown
HY-R00438A	hsa-miR-211-5p agomir	/	Unkown
HY-R02823	mmu-miR-211-3p mimic	/	Unkown
HY-R02823A	mmu-miR-211-3p agomir	/	Unkown
HY-R02824	mmu-miR-211-5p mimic	/	Unkown
HY-R02824A	mmu-miR-211-5p agomir	/	Unkown
HY-R04301	rno-miR-211-3p mimic	/	Unkown
HY-R04301A	rno-miR-211-3p agomir	/	Unkown
HY-RI00433	hsa-miR-211-3p inhibitor	/	Unkown
HY-RI00433A	hsa-miR-211-3p antagomir	/	Unkown
HY-RI00438	hsa-miR-211-5p inhibitor	/	Unkown
HY-RI00438A	hsa-miR-211-5p antagomir	/	Unkown
HY-RI02823	mmu-miR-211-3p inhibitor	/	Unkown
HY-RI02823A	mmu-miR-211-3p antagomir	/	Unkown
HY-RI02824	mmu-miR-211-5p inhibitor	/	Unkown
HY-RI02824A	mmu-miR-211-5p antagomir	/	Unkown
HY-RI04301	rno-miR-211-3p inhibitor	/	Unkown
HY-RI04301A	rno-miR-211-3p antagomir	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Mus musculus	MIR211	MGD	MGI:2676887
Rattus norvegicus	MIR211	RGD	RGD:2325549