MIR29A - microRNA 29a Gene
Also Known as MIRN29; MIRN29A; mir-29a; miRNA29A; hsa-mir-29; hsa-mir-29a
Species: Homo sapiens
About MIR29A
This gene has 1 transcript (splice variant), 76 orthologues and 3 paralogues.
Summary
MicroRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted MicroRNA stem-loop. [provided by RefSeq, Sep 2009]
Related Diseases
| Diseases | Alias | |
|---|---|---|
| Muscular Dystrophy, Duchenne Type |
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| Leukemia, Chronic Lymphocytic |
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| Alzheimer Disease, Familial, 1 |
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| Type 2 Diabetes Mellitus |
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| Hepatocellular Carcinoma |
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| Lung Cancer |
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| Acute Myocardial Infarction |
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| Huntington Disease |
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| Facioscapulohumeral Muscular Dystrophy 1 |
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| Neuroblastoma |
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| Ovarian Serous Carcinoma |
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| Placenta Accreta |
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| Kidney Cancer |
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| Schizophrenia |
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| Oral Squamous Cell Carcinoma |
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| Ovarian Cancer |
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| Prostate Cancer |
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| Colorectal Cancer |
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| Villous Adenoma |
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| Ovarian Disease |
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| Acquired Metabolic Disease |
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| Bile Duct Disease |
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| Carbohydrate Metabolic Disorder |
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| Biliary Tract Disease |
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| Glucose Metabolism Disease |
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| Fatty Liver Disease |
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| Inherited Metabolic Disorder |
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| Lipid Storage Disease |
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| Overnutrition |
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| Bile Duct Cancer |
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| Colorectal Adenoma |
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| Autonomic Nervous System Neoplasm |
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| Peripheral Nervous System Neoplasm |
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| Non-Alcoholic Fatty Liver Disease |
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| Bile Duct Adenocarcinoma |
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| Large Intestine Cancer |
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| Arteries, Anomalies Of |
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| Intestinal Disease |
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| Urinary System Disease |
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| Diabetic Angiopathy |
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| Gastrointestinal System Cancer |
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| Bone Inflammation Disease |
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| Gastrointestinal System Disease |
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| Lymphatic System Disease |
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| Lymphatic System Cancer |
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| Male Reproductive Organ Cancer |
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| Endometrial Squamous Cell Carcinoma |
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| Immune System Disease |
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| Disease Of Mental Health |
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| Male Reproductive System Disease |
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| Reproductive System Disease |
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| Central Nervous System Disease |
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| Biliary Tract Cancer |
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| Myocardial Infarction |
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| Endocrine System Disease |
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| Respiratory System Disease |
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| Endocrine Gland Cancer |
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| Rectum Cancer |
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| Female Reproductive System Disease |
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| Respiratory System Cancer |
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| Diabetes Mellitus |
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| Prostate Disease |
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| Thoracic Cancer |
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| Cerebrovascular Disease |
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| Prediabetes Syndrome |
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| Lysosomal Storage Disease |
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| Burkitt Lymphoma |
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| Sensory System Disease |
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| Colorectal Adenocarcinoma |
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| Uterine Anomalies |
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| Toxic Encephalopathy |
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| Peripheral Nervous System Disease |
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| Retinal Disease |
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| Cell Type Benign Neoplasm |
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| Alcohol Use Disorder |
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| Disease By Infectious Agent |
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| Bladder Disease |
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| Stomach Disease |
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| Colonic Disease |
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| Hematologic Cancer |
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| Breast Disease |
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| Connective Tissue Cancer |
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| Spinal Cord Disease |
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| Spinal Disease |
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| Hypertension, Essential |
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| Pancreas Disease |
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| Connective Tissue Disease |
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| Nervous System Disease |
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| Cardiovascular System Disease |
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| Left Ventricular Noncompaction |
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| Esophageal Cancer |
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| Leukemia, Acute Myeloid |
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| Eye Disease |
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| Osteoporosis |
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| Body Mass Index Quantitative Trait Locus 11 |
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| Lipoprotein Quantitative Trait Locus |
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| Immune Deficiency Disease |
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| Hypertrophic Cardiomyopathy |
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| Aortic Aneurysm, Familial Thoracic 1 |
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Orthologs Information
| Species | Symbol | Source | ID |
|---|---|---|---|
| Rattus norvegicus | MIR29A | RGD | RGD:2325393 |
| Mus musculus | MIR29A | MGD | MGI:2676904 |