Myo1a - myosin IA Gene

Also Known as Myhl; BBM-I

Species: Mus musculus

Gene Type: protein coding
Gene ID: 432516

Summary

Enables actin filament binding activity. Acts upstream of or within microvillus assembly. Located in several cellular components, including basal plasma membrane; brush border; and lateral plasma membrane. Is expressed in several structures, including inner ear and intestine. Human ortholog(s) of this gene implicated in autosomal dominant nonsyndromic deafness 48 and sensorineural hearing loss. Orthologous to human MYO1A (Myosin IA). [provided by Alliance of Genome Resources, Apr 2022]

Myo1a Products (1)

mRNA Protein Name
NM_001081219.2 NP_001074688.1 unconventional myosin-Ia

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables actin filament binding IDA
IDA: Inferred from direct assay
20089841 MGI
Biological Process GO Annotation Evidence References Source
acts upstream of or within cell projection organization IMP
IMP: Inferred from mutant phenotype
15758024 MGI
acts upstream of or within microvillus assembly IMP
IMP: Inferred from mutant phenotype
15758024 MGI
Cellular Component GO Annotation Evidence References Source
located in apical plasma membrane IDA
IDA: Inferred from direct assay
9933937 MGI
located in basal plasma membrane IDA
IDA: Inferred from direct assay
9933937 MGI
located in brush border IDA
IDA: Inferred from direct assay
15758024 MGI
located in lateral plasma membrane IDA
IDA: Inferred from direct assay
9933937 MGI
located in microvillus IDA
IDA: Inferred from direct assay
9933937 MGI
located in plasma membrane raft IDA
IDA: Inferred from direct assay
20089841 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

unconventional myosin-Ia

  • BBMI

  • MIHC

  • brush border myosin 1

  • brush border myosin I

  • myosin I heavy chain

  • myosin, heavy polypeptide-like (110kD)

  • myosin-Ia

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS08937 MYO1A Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Myo1a NCBI NCBI:4640