PLK3 - polo like kinase 3 Gene

Species: Canis lupus familiaris (sub-species: familiaris)

Gene Type: protein coding
Gene ID: 475380

About PLK3

Primary_assembly 15: 15,674,432-15,679,641 reverse strand.ROS_Cfam_1.0:CM025114.1

This gene has 2 transcripts (splice variants), 203 orthologues and 4 paralogues.

PLK3 Products (1)

mRNA Protein Name
XM_038687884.1 XP_038543812.1 serine/threonine-protein kinase PLK3

PLK3 Protein Structure

PKc_like

PKc_like: cl21453 (59 - 313)

POLO_box_1

POLO_box_1: cd13118 (459 - 547)

POLO_box_2

POLO_box_2: cd13117 (560 - 627)

  • 0
  • 100
  • 200
  • 300
  • 400
  • 500
  • 600
  • 646 a.a.
Protein Preferred Names Protein Names

serine/threonine-protein kinase PLK3

Related Agents

  • Approval
  • Clinical Phase
  • Pre-clinical Phase

Approval

Bioactive Molecules (2)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-12137 Volasertib Inhibitor 99.97% Yes
HY-12137A Volasertib trihydrochloride Inhibitor 99.12% Yes

Clinical Phase

Bioactive Molecules (5)
Cat. No. Product Name Effect
Purity Phase
HY-50698 BI 2536 Inhibitor 99.95% Phase 2
HY-147298 Plogosertib Inhibitor 98.59% Phase 2
HY-15160 TAK-960 Inhibitor 99.75% Phase 1
HY-15160B TAK-960 dihydrochloride Inhibitor 99.15% Phase 1
HY-15160A TAK-960 hydrochloride Inhibitor / Phase 1

Pre-clinical Phase

Bioactive Molecules (16)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-10197 Wortmannin Inhibitor 99.86% Unkown
HY-100789 ON1231320 Inhibitor 99.90% Unkown
HY-11003 GW843682X Inhibitor 99.89% Unkown
HY-12134 Poloxin Inhibitor 98.05% Unkown
HY-108597 TC-S 7005 Inhibitor 99.68% Unkown
HY-15158 SBE13 Hydrochloride Inhibitor 98.56% Unkown
HY-18009 (Z)-LFM-A13 Inhibitor 99.80% Unkown
HY-110002 LFM-A13 Inhibitor 99.65% Unkown
HY-173212 PLK1-IN-13 Inhibitor / Unkown
HY-149100 PLK1-IN-6 Inhibitor / Unkown
HY-15158A SBE13 Inhibitor / Unkown
HY-172364 PLK1-IN-12 Inhibitor / Unkown
HY-115589 YLT-11 Inhibitor / Unkown
HY-111090 GSK461364 analogue 1 Inhibitor / Unkown
HY-181051 PLK1-IN-16 Inhibitor / Unkown
HY-181030 BDE30671203 Inhibitor / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens PLK3 NCBI NCBI:1263