APC - APC regulator of WNT signaling pathway Gene
Species: Canis lupus familiaris (sub-species: familiaris)
About APC
This gene has 5 transcripts (splice variants), 169 orthologues, 1 paralogue and is associated with 1 phenotype.
APC Products (9)
| mRNA | Protein | Name |
|---|---|---|
| XM_038660623.1 | XP_038516551.1 | adenomatous polyposis coli protein isoform X4 |
| XM_038660624.1 | XP_038516552.1 | adenomatous polyposis coli protein isoform X4 |
| XM_038660621.1 | XP_038516549.1 | adenomatous polyposis coli protein isoform X2 |
| XM_038660626.1 | XP_038516554.1 | adenomatous polyposis coli protein isoform X6 |
| XM_038660619.1 | XP_038516547.1 | adenomatous polyposis coli protein isoform X1 |
| XM_038660625.1 | XP_038516553.1 | adenomatous polyposis coli protein isoform X5 |
| XM_038660620.1 | XP_038516548.1 | adenomatous polyposis coli protein isoform X1 |
| XM_038660618.1 | XP_038516546.1 | adenomatous polyposis coli protein isoform X1 |
| XM_038660622.1 | XP_038516550.1 | adenomatous polyposis coli protein isoform X3 |
APC Protein Structure
APC_N_CC: pfam16689 (3 - 54)
Smc: cl34174 (13 - 261)
Suppressor_APC: pfam11414 (126 - 206)
ARM: smart00185 (339 - 391)
APC_rep: pfam18797 (392 - 465)
ARM: sd00043 (489 - 525)
ARM: smart00185 (529 - 570)
ARM: sd00043 (533 - 570)
ARM: sd00043 (580 - 612)
ARM: sd00043 (620 - 661)
ARM: smart00185 (666 - 706)
ARM: sd00043 (670 - 704)
Arm: pfam00514 (708 - 748)
ARM: sd00043 (712 - 748)
Arm_APC_u3: pfam16629 (749 - 1036)
APC_u5: pfam16630 (1053 - 1152)
APC_r: pfam05923 (1274 - 1291)
APC_u9: pfam16633 (1300 - 1385)
APC_r: pfam05923 (1388 - 1410)
APC_r: pfam05923 (1654 - 1677)
APC_u13: pfam16634 (1679 - 1732)
SAMP: pfam05924 (1733 - 1754)
APC_u14: pfam16635 (1763 - 1856)
APC_r: pfam05923 (1858 - 1882)
APC_u15: pfam16636 (1884 - 1964)
SAMP: pfam05924 (2051 - 2070)
APC_basic: pfam05956 (2241 - 2586)
EB1_binding: pfam05937 (2688 - 2861)
- 0
- 500
- 1000
- 1500
- 2000
- 2500
- 2862 a.a.
| Protein Preferred Names | Protein Names | |
|---|---|---|
|
adenomatous polyposis coli protein |
|
Related Agents
- Approval
- Pre-clinical Phase
Approval
| Cat. No. | Product Name |
Effect
|
Purity |
Rare Diseases
|
|---|---|---|---|---|
| HY-112968 | Human protein C | / | Unkown |
Pre-clinical Phase
| Cat. No. | Product Name |
Effect
|
Purity |
Rare Diseases
|
|---|---|---|---|---|
| HY-124955 | proTAME | Inhibitor | 98.20% | Unkown |
| HY-110287 | Apcin | Inhibitor | 99.62% | Unkown |
| HY-13255 | TAME | Inhibitor | 99.51% | Unkown |
| HY-130841 | Apcin-A | Inhibitor | 98.0% | Unkown |
| HY-P1918 | Activated Protein C (390-404), human | 98.74% | Unkown | |
| HY-13255A | TAME hydrochloride | Inhibitor | 98.31% | Unkown |
| HY-122142A | Pyr-Pro-Arg-pNA (hydrochloride) | Substrate | 99.24% | Unkown |
| HY-182052 | Ferroptosis inducer-16 | Inhibitor | / | Unkown |
| HY-112968A | Bovine Protein C | / | Unkown | |
| HY-122142 | Pyr-Pro-Arg-pNA | Substrate | / | Unkown |
| HY-126016 | MAI-400 | Inhibitor | / | Unkown |
| HY-P1918A | Activated Protein C (390-404), human TFA | / | Unkown | |
| HY-116473 | CFM-1 | Antagonist | / | Unkown |
| HY-179012 | CDC20/HSP90-IN-1 | Inhibitor | / | Unkown |
| HY-172401 | CDC20-IN-2 | Inhibitor | / | Unkown |
| HY-W614725 | Apcin-A monohydrochloride | Inhibitor | / | Unkown |
| Cat. No. | Product Name |
Effect
|
Purity |
Rare Diseases
|
|---|---|---|---|---|
| HY-P992193 | Anti-B7-H7 Antibody | / | Unkown |
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