2. Gene
  3. EZH1 - enhancer of zeste 1 polycomb repressive complex 2 subunit Gene

EZH1 - enhancer of zeste 1 polycomb repressive complex 2 subunit Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Canis lupus familiaris (sub-species: familiaris)
Gene ID: 480516 | Gene type: protein coding

About EZH1

Primary_assembly 9: 20,981,878-21,011,945 forward strand.ROS_Cfam_1.0:CM025108.1

This gene has 3 transcripts (splice variants), 234 orthologues and 19 paralogues.

EZH1 Products(3)

mRNA Protein Name
XM_038676407.1 XP_038532335.1 histone-lysine N-methyltransferase EZH1
XM_038676409.1 XP_038532337.1 histone-lysine N-methyltransferase EZH1
XM_038676408.1 XP_038532336.1 histone-lysine N-methyltransferase EZH1

EZH1 Protein Structure

EZH2_WD-Binding

EZH2_WD-Binding: pfam11616 (38 - 67)

PRC2_HTH_1

PRC2_HTH_1: pfam18118 (158 - 261)

SANT

SANT: cd00167 (432 - 473)

SET

SET: cl34524 (462 - 726)

SET_EZH1

SET_EZH1: cd19217 (607 - 742)

  • 0
  • 200
  • 400
  • 600
  • 747 a.a.
Protein Preferred Names Protein Names

histone-lysine N-methyltransferase EZH1

enhancer of zeste homolog 1

Related Agents

Approval
Bioactive Molecules (2)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-109108 Valemetostat Inhibitor 99.84% Unkown
HY-109108A Valemetostat tosylate Inhibitor 99.84% Unkown
Clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Phase
HY-145602 Tulmimetostat Inhibitor 99.79% Phase 2
Pre-clinical Phase
Bioactive Molecules (6)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-15646 UNC1999 Inhibitor 99.87% Unkown
HY-141877 MS4322 Degrader 99.14% Unkown
HY-141877B MS4322 (isomer) 99.87% Unkown
HY-144881 (S)-HH2853 Inhibitor / Unkown
HY-181327 PROTAC EZH2 Degrader-26 Degrader / Unkown
HY-180553 NSD2-IN-6 Inhibitor / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens EZH1 NCBI NCBI:2145