ITK - IL2 inducible T cell kinase Gene

Species: Canis lupus familiaris (sub-species: familiaris)

Gene Type: protein coding
Gene ID: 489159

About ITK

Primary_assembly 4: 53,340,020-53,402,842 reverse strand.ROS_Cfam_1.0:CM025103.1

This gene has 1 transcript (splice variant), 206 orthologues and 32 paralogues.

ITK Products (1)

mRNA Protein Name
XM_038663529.1 XP_038519457.1 tyrosine-protein kinase ITK/TSK isoform X1

ITK Protein Structure

PH_Btk

PH_Btk: cd01238 (6 - 147)

SH3_ITK

SH3_ITK: cd11908 (173 - 228)

SH2_Tec_Itk

SH2_Tec_Itk: cd10396 (231 - 339)

PTKc_Itk

PTKc_Itk: cd05112 (357 - 612)

  • 0
  • 100
  • 200
  • 300
  • 400
  • 500
  • 620 a.a.
Protein Preferred Names Protein Names

tyrosine-protein kinase ITK/TSK

LOW QUALITY PROTEIN: tyrosine-protein kinase ITK/TSK

Related Agents

  • Clinical Phase
  • Pre-clinical Phase

Clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Phase
HY-109078 Vecabrutinib Inhibitor 99.76% Phase 2

Pre-clinical Phase

Bioactive Molecules (28)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-150298 Soquelitinib Inhibitor 99.98% Unkown
HY-11092 BMS-509744 Inhibitor 98.05% Unkown
HY-12680 PRN694 Inhibitor ≥99.0% Unkown
HY-108691 PF-06465469 Inhibitor 99.48% Unkown
HY-148065 FMF-06-098-1 Inhibitor 98.77% Unkown
HY-101321A Immepip dihydrobromide Degrader 99.98% Unkown
HY-128726 ITK inhibitor 2 Inhibitor 99.50% Unkown
HY-12410 GNE-9822 Inhibitor 98.47% Unkown
HY-169396 TAE648 Ligand 99.50% Unkown
HY-120559 GSK-2250665A Inhibitor 96.35% Unkown
HY-185206 BSJ-05-037 Degrader 99.83% Unkown
HY-174280 Modzatinib Inhibitor / Unkown
HY-150023 BI-1622 Inhibitor 98.02% Unkown
HY-146672 ITK inhibitor 6 Inhibitor / Unkown
HY-13232 ITK antagonist Inhibitor / Unkown
HY-174903 ITK-IN-6 Inhibitor 99.02% Unkown
HY-149917 PROTAC ITK degrader 1 Degrader / Unkown
HY-N6857C (±)-Armepavine hydrochloride / Unkown
HY-184275 ITK-IN-7 Inhibitor / Unkown
HY-16984 GNE-4997 Inhibitor / Unkown
HY-168963 PROTAC BTK Degrader-13 Inhibitor / Unkown
HY-182335 PF-07245303 Inhibitor / Unkown
HY-168387 ITK ligand 1 Inhibitor / Unkown
HY-153322 ITK degrader 2 Degrader / Unkown
HY-141864 ITK/TRKA-IN-1 Inhibitor / Unkown
HY-146671 ITK inhibitor 5 Inhibitor / Unkown
HY-E70833 ITK Recombinant Human Active Protein Kinase / Unkown
HY-143901 EGFR-IN-40 Inhibitor / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens ITK NCBI NCBI:3702