2. Gene
  3. ITK - IL2 inducible T cell kinase Gene

ITK - IL2 inducible T cell kinase Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Canis lupus familiaris (sub-species: familiaris)
Gene ID: 489159 | Gene type: protein coding

About ITK

Primary_assembly 4: 53,340,020-53,402,842 reverse strand.ROS_Cfam_1.0:CM025103.1

This gene has 1 transcript (splice variant), 206 orthologues and 32 paralogues.

ITK Products(1)

mRNA Protein Name
XM_038663529.1 XP_038519457.1 tyrosine-protein kinase ITK/TSK isoform X1

ITK Protein Structure

PH_Btk

PH_Btk: cd01238 (6 - 147)

SH3_ITK

SH3_ITK: cd11908 (173 - 228)

SH2_Tec_Itk

SH2_Tec_Itk: cd10396 (231 - 339)

PTKc_Itk

PTKc_Itk: cd05112 (357 - 612)

  • 0
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  • 500
  • 620 a.a.
Protein Preferred Names Protein Names

tyrosine-protein kinase ITK/TSK

LOW QUALITY PROTEIN: tyrosine-protein kinase ITK/TSK

Related Agents

Clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Phase
HY-109078 Vecabrutinib Inhibitor 99.76% Phase 2
Pre-clinical Phase
Bioactive Molecules (26)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-150298 Soquelitinib Inhibitor 99.71% Unkown
HY-11092 BMS-509744 Inhibitor 98.05% Unkown
HY-12680 PRN694 Inhibitor ≥99.0% Unkown
HY-108691 PF-06465469 Inhibitor 99.48% Unkown
HY-101321A Immepip dihydrobromide Degrader 99.98% Unkown
HY-128726 ITK inhibitor 2 Inhibitor 99.50% Unkown
HY-148065 FMF-06-098-1 Inhibitor 98.77% Unkown
HY-12410 GNE-9822 Inhibitor 98.47% Unkown
HY-120559 GSK-2250665A Inhibitor 96.35% Unkown
HY-185206 BSJ-05-037 Degrader 99.83% Unkown
HY-174280 Modzatinib Inhibitor / Unkown
HY-150023 BI-1622 Inhibitor 97.05% Unkown
HY-146672 ITK inhibitor 6 Inhibitor / Unkown
HY-13232 ITK antagonist Inhibitor / Unkown
HY-174903 ITK-IN-6 Inhibitor 99.02% Unkown
HY-149917 ITK degrader 1 Degrader / Unkown
HY-16984 GNE-4997 Inhibitor / Unkown
HY-N6857C (±)-Armepavine hydrochloride / Unkown
HY-168387 ITK ligand 1 Inhibitor / Unkown
HY-146671 ITK inhibitor 5 Inhibitor / Unkown
HY-182335 PF-07245303 Inhibitor / Unkown
HY-143901 EGFR-IN-40 Inhibitor / Unkown
HY-153322 ITK degrader 2 Degrader / Unkown
HY-E70833 ITK Recombinant Human Active Protein Kinase / Unkown
HY-141864 ITK/TRKA-IN-1 Inhibitor / Unkown
HY-168963 PROTAC BTK Degrader-13 Inhibitor / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens ITK NCBI NCBI:3702
Mus musculus ITK NCBI NCBI:16428