ITK inhibitor 2
Based on 2 publication(s) in Google Scholar
ITK inhibitor 2 is a ITK inhibitor with an IC50 of 2 nM. ITK inhibitor 2 is used for research on inflammatory diseases, allergic diseases, autoimmune diseases and transplant rejection.
For research use only. We do not sell to patients.
- Purity: 99.50%
- CAS No.: 1309784-09-5
- Formula: C25H33N5O2
- Molecular Weight:435.56
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Storage:Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
Publications Citing Use of MedChemExpress (MCE) ITK inhibitor 2
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Biological Activity
IC50: 2 nM (ITK inhibitor 2)[1]
Chemical Information
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CAS No. 1309784-09-5
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Appearance Solid
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Molecular Weight 435.56
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Formula C25H33N5O2
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Color Off-white to gray
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SMILES
CC1(CC2=C(CC1)C(C(NC3=C4)=CC3=CC=C4N(C)C([C@@H](N5CCOCC5)C)=O)=NN2)C
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
Publications (2)
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Journal Impact Factor
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Most Recent
Solvent & Solubility
DMSO : 100 mg/mL (229.59 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (273 KB)
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SDS (251 KB)
- English - EN (251 KB)
- Français - FR (251 KB)
- Deutsch - DE (251 KB)
- Norwegian - NO (251 KB)
- Español - ES (251 KB)
- Swedish - SV (251 KB)
- Italian - IT (251 KB)
- Korean - KR (251 KB)
- Portuguese - PT (251 KB)
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Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 2.2959 mL | 11.4795 mL | 22.9589 mL | 57.3974 mL |
| 5 mM | 0.4592 mL | 2.2959 mL | 4.5918 mL | 11.4795 mL | |
| 10 mM | 0.2296 mL | 1.1479 mL | 2.2959 mL | 5.7397 mL | |
| 15 mM | 0.1531 mL | 0.7653 mL | 1.5306 mL | 3.8265 mL | |
| 20 mM | 0.1148 mL | 0.5740 mL | 1.1479 mL | 2.8699 mL | |
| 25 mM | 0.0918 mL | 0.4592 mL | 0.9184 mL | 2.2959 mL | |
| 30 mM | 0.0765 mL | 0.3826 mL | 0.7653 mL | 1.9132 mL | |
| 40 mM | 0.0574 mL | 0.2870 mL | 0.5740 mL | 1.4349 mL | |
| 50 mM | 0.0459 mL | 0.2296 mL | 0.4592 mL | 1.1479 mL | |
| 60 mM | 0.0383 mL | 0.1913 mL | 0.3826 mL | 0.9566 mL | |
| 80 mM | 0.0287 mL | 0.1435 mL | 0.2870 mL | 0.7175 mL | |
| 100 mM | 0.0230 mL | 0.1148 mL | 0.2296 mL | 0.5740 mL |