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Referencia número: HY-120559

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GSK-2250665A

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Based on 1 Customer Validation

GSK-2250665A (Compound 13) is a selective Itk inhibitor with a pK_i of 9.2.

Para uso exclusivo en investigación. No vendemos a pacientes.

Pureza: 96.35%
No. CAS: 1246030-96-5
Fòrmula: C₂₆H₂₉N₅OS
Peso molecular:459.61

Almacenamiento:

Store at room temperature, keep dry and cool.

In solvent -80°C, 1 year , -20°C, 6 months

GSK-2250665A Chemical Structure

No. CAS: 1246030-96-5

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Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Actividad biológica
- Descripciòn
- In Vitro
Chemical Information
Pureza y Documentación
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Actividad biológica

Descripciòn

GSK-2250665A (Compound 13) is a selective Itk inhibitor with a pK_i of 9.2.

In Vitro

GSK-2250665A (Compound 13) achieves a pIC₅₀ of 7.3 in the cell assay, measuring inhibition of IFNγ production from PBMCs (Peripheral Blood Mononuclear Cells) ^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Chemical Information

No. CAS 1246030-96-5
Appearance Solid
Peso molecular 459.61
Fòrmula C₂₆H₂₉N₅OS
Color White to off-white
SMILES

CCC1=CC=C2C(SC(NC3=NC(N[C@H]4CC[C@@H](CC4)O)=NC(CC5=CC=CC=C5)=C3)=N2)=C1
Envío

Room temperature in continental US; may vary elsewhere.

Almacenamiento

Store at room temperature, keep dry and cool

In solvent	-80°C	1 year
	-20°C	6 months

Pureza y Documentación

Select Batch:

Pureza: 99.98%

Assay: 99.98%

ee.: 99.98%

Ficha de datos (268 KB)
SDS (251 KB)
- English - EN (251 KB)
- Français - FR (251 KB)
- Deutsch - DE (251 KB)
- Norwegian - NO (251 KB)
- Español - ES (251 KB)
- Swedish - SV (251 KB)
- Italian - IT (251 KB)
- Korean - KR (251 KB)
- Portuguese - PT (251 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Instrucciones de manejo (2659 KB)

Referencias

[1]. Alder CM, et al. Identification of a Novel and Selective Series of Itk Inhibitors via a Template-Hopping Strategy. ACS Med Chem Lett. 2013 Aug 12;4(10):948-52. [Content Brief]

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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100 mg

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GSK-2250665A

Bioactive Compound Library Max

Bioactive Compound Library

Immunology/Inflammation Compound Library

Kinase Inhibitor Library

Protein Tyrosine Kinase Compound Library

Highly Selective Inhibitors Library

Serine/Threonine Kinase Inhibitor Library

MCE Bioactive Compound Library

Protein Kinase Compound Library

High-Throughput Bioactive Compound Library

Actividad biológica

Chemical Information

Pureza y Documentación

Referencias

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Help & FAQs

GSK-2250665A

Bioactive Compound Library Max

Bioactive Compound Library

Immunology/Inflammation Compound Library

Kinase Inhibitor Library

Protein Tyrosine Kinase Compound Library

Highly Selective Inhibitors Library

Serine/Threonine Kinase Inhibitor Library

MCE Bioactive Compound Library

Protein Kinase Compound Library

High-Throughput Bioactive Compound Library

Actividad biológica

Chemical Information

Pureza y Documentación

Referencias

Calculators

Help & FAQs

GSK-2250665A Related Classifications

HY-120559 Related Classifications