1. Protein Tyrosine Kinase/RTK
  2. Itk
  3. PF-06465469

PF-06465469 

Cat. No.: HY-108691
Handling Instructions

PF-06465469 is a covalent inhibitor of ITK with an IC50 of 2 nM.

For research use only. We do not sell to patients.

PF-06465469 Chemical Structure

PF-06465469 Chemical Structure

CAS No. : 1407966-77-1

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Description

PF-06465469 is a covalent inhibitor of ITK with an IC50 of 2 nM[1].

IC50 & Target

IC50: 2 nM (ITK)[1]

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

References
Molecular Weight

523.63

Formula

C₃₀H₃₃N₇O₂

CAS No.

1407966-77-1

SMILES

O=C(NC1=CC=C(C(C)C)C(C)=C1)C2=CC=CC(C3=NN([[email protected]]4CN(C(C=C)=O)CCC4)C5=NC=NC(N)=C53)=C2

Shipping

Room temperature in continental US; may vary elsewhere

  • Molarity Calculator

  • Dilution Calculator

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass   Concentration   Volume   Molecular Weight *
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The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2

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Product Name:
PF-06465469
Cat. No.:
HY-108691
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PF-06465469

Cat. No.: HY-108691