Brsk1 - BR serine/threonine kinase 1 Gene

Also Known as Sad-b; RGD1563268

Species: Rattus norvegicus

Gene Type: protein coding
Gene ID: 499073

Summary

Enables protein serine/threonine kinase activity. Involved in neurotransmitter secretion. Located in distal axon and synaptic vesicle. Orthologous to human BRSK1 (BR serine/threonine kinase 1). [provided by Alliance of Genome Resources, Apr 2022]

Brsk1 Products (1)

mRNA Protein Name
NM_001127337.1 NP_001120809.1 serine/threonine-protein kinase BRSK1

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables protein binding IPI
IPI: Inferred from physical interaction
16630837 RGD
enables protein serine/threonine kinase activity IDA
IDA: Inferred from direct assay
16630837 RGD
enables protein serine/threonine kinase activity IMP
IMP: Inferred from mutant phenotype
25788287 RGD
Biological Process GO Annotation Evidence References Source
involved in neurotransmitter secretion IMP
IMP: Inferred from mutant phenotype
16630837 RGD
involved in regulation of synaptic vesicle priming IDA
IDA: Inferred from direct assay
16630837 RGD
involved in regulation of synaptic vesicle priming IEP
IEP: Inferred from expression pattern
16630837 RGD
involved in regulation of synaptic vesicle priming IMP
IMP: Inferred from mutant phenotype
16630837 RGD
Cellular Component GO Annotation Evidence References Source
is active in cholinergic synapse IDA
IDA: Inferred from direct assay
16630837 RGD
is active in cholinergic synapse IMP
IMP: Inferred from mutant phenotype
16630837 RGD
located in distal axon IMP
IMP: Inferred from mutant phenotype
25788287 RGD
is active in postsynaptic density IDA
IDA: Inferred from direct assay
16630837 RGD
is active in synaptic vesicle IDA
IDA: Inferred from direct assay
16630837 RGD
located in synaptic vesicle IDA
IDA: Inferred from direct assay
16630837 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

serine/threonine-protein kinase BRSK1

  • BR serine/threonine-protein kinase 1

  • brain-specific serine/threonine-protein kinase 1

  • serine/threonine-protein kinase SAD-B

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS01637 BRSK1 Human Pre-designed siRNA Set A / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Brsk1 NCBI NCBI:84446