Slc6a12 - solute carrier family 6 member 12 Gene

Also Known as BGT1; Gat1; VGAT; RNU28927

Species: Rattus norvegicus

Gene Type: protein coding
Gene ID: 50676

Summary

Predicted to enable gamma-aminobutyric acid:sodium symporter activity. Involved in cellular hyperosmotic response; cellular water homeostasis; and response to organic substance. Is integral component of membrane. Orthologous to human SLC6A12 (solute carrier family 6 member 12). [provided by Alliance of Genome Resources, Apr 2022]

Slc6a12 Products (1)

mRNA Protein Name
NM_017335.1 NP_059031.1 sodium- and chloride-dependent betaine transporter

Gene Ontology

  • Biological Process
Biological Process GO Annotation Evidence References Source
involved in cellular hyperosmotic response IEP
IEP: Inferred from expression pattern
17022965 RGD
involved in intracellular water homeostasis IDA
IDA: Inferred from direct assay
20394832 RGD
involved in response to kainic acid IEP
IEP: Inferred from expression pattern
15248296 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

sodium- and chloride-dependent betaine transporter

  • Betaine/GABA transporter 1

  • GABA transporter 1

  • Na(+)/Cl(-) betaine/GABA transporter

  • solute carrier family 6 (neurotransmitter transporter), member 12

  • solute carrier family 6 (neurotransmitter transporter, betaine/GABA), member 12

  • vesicular GABA transp

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS13298 SLC6A12 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Slc6a12 NCBI NCBI:6539