RNFT1 - ring finger protein, transmembrane 1 Gene

Homo sapiens

Also known as PTD016

Gene ID: 51136 | Gene type: protein coding

About RNFT1

Cytogenetic location: 17q23.1 Genomic coordinates (GRCh38): 17:59,952,240-59,964,740 (from NCBI)

This gene has 9 transcripts (splice variants), 208 orthologues and 1 paralogue. Broad expression in testis (RPKM 54.5), appendix (RPKM 8.9) and 22 other tissues.

Summary

Enables ubiquitin binding activity and ubiquitin protein ligase activity. Involved in positive regulation of ERAD pathway and protein autoubiquitination. Located in endoplasmic reticulum. [provided by Alliance of Genome Resources, Apr 2022]

RNFT1 Products(1)

mRNA	Protein	Name
NM_016125.4	NP_057209.3	E3 ubiquitin-protein ligase RNFT1

RNFT1 Protein Structure

zf-C3HC4_3

0
100
200
300
400
435 a.a.

Protein Preferred Names

Protein Names

E3 ubiquitin-protein ligase RNFT1

RING finger and transmembrane domain-containing protein 1

Related Diseases

Diseases

Alias

Papillary Cystadenocarcinoma

Cystadenocarcinoma, Papillary

Diseases	Alias
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS12098	RNFT1 Human Pre-designed siRNA Set A		/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Bos taurus	RNFT1	VGNC	VGNC:34074
Mus musculus	RNFT1	MGD	MGI:1924142
Canis familiaris	RNFT1	VGNC	VGNC:45677
Felis catus	RNFT1	VGNC	VGNC:64707
Rattus norvegicus	RNFT1	RGD	RGD:1562411
Macaca mulatta	RNFT1	VGNC	VGNC:76865

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