C1RL - complement C1r subcomponent like Gene

Homo sapiens

Also known as C1RL1; C1RLP; CLSPa; C1r-LP

Gene ID: 51279 | Gene type: protein coding

About C1RL

Cytogenetic location: 12p13.31 Genomic coordinates (GRCh38): 12:7,094,554-7,109,214 (from NCBI)

This gene has 12 transcripts (splice variants), 1 gene allele, 199 orthologues and 16 paralogues. Ubiquitous expression in liver (RPKM 37.4), adrenal (RPKM 16.4) and 22 other tissues.

Summary

Predicted to enable serine-type endopeptidase activity. Predicted to be involved in zymogen activation. Located in extracellular exosome. [provided by Alliance of Genome Resources, Apr 2022]

C1RL Products(4)

mRNA	Protein	Name
NM_001297640.2	NP_001284569.1	complement C1r subcomponent-like protein isoform 2 precursor
NM_001297642.2	NP_001284571.1	complement C1r subcomponent-like protein isoform 3 precursor
NM_001297643.2	NP_001284572.1	complement C1r subcomponent-like protein isoform 4 precursor
NM_016546.4	NP_057630.2	complement C1r subcomponent-like protein isoform 1 precursor

C1RL Protein Structure

CUB

Trypsin

0
100
200
300
400
487 a.a.

Protein Preferred Names

Protein Names

complement C1r subcomponent-like protein

C1r-like protein

Related Diseases

Diseases

Alias

Ovary Adenocarcinoma

Ovarian Adenocarcinoma	Adenocarcinoma Of The Ovary
Ovarian Adenoacanthoma	Adenocarcinoma Of Ovary

Breast Adenocarcinoma

Mammary Adenocarcinoma

Adenocarcinoma Of Breast

Diseases	Alias
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS01736	C1RL Human Pre-designed siRNA Set A		/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Macaca mulatta	C1RL	VGNC	VGNC:108329
Mus musculus	C1RL	MGD	MGI:2660692
Bos taurus	C1RL	VGNC	VGNC:26629
Canis familiaris	C1RL	VGNC	VGNC:38587
Rattus norvegicus	C1RL	RGD	RGD:1302936