C1RL - complement C1r subcomponent like Gene

Also Known as C1RL1; C1RLP; CLSPa; C1r-LP

Species: Homo sapiens

Gene Type: protein coding
Gene ID: 51279

About C1RL

Cytogenetic location: 12p13.31 Genomic coordinates (GRCh38): 12:7,094,554-7,109,214 (from NCBI)

This gene has 12 transcripts (splice variants), 1 gene allele, 199 orthologues and 16 paralogues. Ubiquitous expression in liver (RPKM 37.4), adrenal (RPKM 16.4) and 22 other tissues.

Summary

Predicted to enable serine-type endopeptidase activity. Predicted to be involved in zymogen activation. Located in extracellular exosome. [provided by Alliance of Genome Resources, Apr 2022]

C1RL Products (4)

mRNA Protein Name
NM_001297640.2 NP_001284569.1 complement C1r subcomponent-like protein isoform 2 precursor
NM_001297642.2 NP_001284571.1 complement C1r subcomponent-like protein isoform 3 precursor
NM_001297643.2 NP_001284572.1 complement C1r subcomponent-like protein isoform 4 precursor
NM_016546.4 NP_057630.2 complement C1r subcomponent-like protein isoform 1 precursor

C1RL Protein Structure

CUB

CUB: CUB domain (47 - 148)

Trypsin

Trypsin: Trypsin (247 - 479)

  • 0
  • 100
  • 200
  • 300
  • 400
  • 487 a.a.
Protein Preferred Names Protein Names

complement C1r subcomponent-like protein

  • C1r-like protein

Related Diseases

Diseases Alias
Ovary Adenocarcinoma

  • Ovarian Adenocarcinoma

  • Adenocarcinoma Of The Ovary

  • Ovarian Adenoacanthoma

  • Adenocarcinoma Of Ovary
Breast Adenocarcinoma

  • Mammary Adenocarcinoma

  • Adenocarcinoma Of Breast
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS01736 C1RL Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Macaca mulatta C1RL VGNC VGNC:108329
Mus musculus C1RL MGD MGI:2660692
Bos taurus C1RL VGNC VGNC:26629
Canis familiaris C1RL VGNC VGNC:38587
Rattus norvegicus C1RL RGD RGD:1302936
Others C1RL NCBI