EMCN - endomucin Gene

Also Known as EMCN2; MUC14

Species: Homo sapiens

Gene Type: protein coding
Gene ID: 51705

About EMCN

Cytogenetic location: 4q24 Genomic coordinates (GRCh38): 4:100,395,341-100,518,022 (from NCBI)

This gene has 10 transcripts (splice variants) and 106 orthologues. Broad expression in kidney (RPKM 11.5), lung (RPKM 11.1) and 19 other tissues.

Summary

EMCN is a mucin-like sialoglycoprotein that interferes with the assembly of focal adhesion complexes and inhibits interaction between cells and the extracellular matrix (Kinoshita et al., 2001 [PubMed 11418125]).[supplied by OMIM, Mar 2008]

EMCN Products (2)

mRNA Protein Name
NM_001159694.2 NP_001153166.1 endomucin isoform 2 precursor
NM_016242.4 NP_057326.2 endomucin isoform 1 precursor

Gene Ontology

  • Molecular Function
Molecular Function GO Annotation Evidence References Source
enables protein binding IPI
IPI: Inferred from physical interaction
32296183 GOA
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

EMCN Protein Structure

Endomucin

Endomucin: Endomucin (1 - 261)

  • 0
  • 100
  • 200
  • 261 a.a.
Protein Preferred Names Protein Names

endomucin

  • MUC-14

Related Diseases

Diseases Alias
Nephrotic Syndrome, Type 10

  • NPHS10

  • Nephrotic Syndrome Type 10

  • Idiopathic Steroid-Sensitive Nephrotic Syndrome

  • Nephrotic Syndrome 10
Hypotrichosis-Lymphedema-Telangiectasia-Renal Defect Syndrome

  • Glomerulonephritis With Sparse Hair And Telangiectases

  • Telangiectatic Membranoproliferative Glomerulonephritis

  • HLTRS

  • Hypotrichosis-Lymphedema-Telangiectasia-Membranoproliferative Glomerulonephritis Syndrome

  • Hlt-Renal Defect Syndrome

  • Glomerulonephritis Sparse Hair Telangiectases
Gastric Cancer

  • Stomach Cancer

  • Gastric Carcinoma

  • Stomach Carcinoma

  • Gastric Cancer, Somatic

  • Gastric Neoplasm

  • Carcinoma Of Stomach

  • Stomach Neoplasms

  • Malignant Neoplasm Of Stomach

  • Gastric Cancer Risk After H. Pylori Infection

  • Cancer Of The Stomach

  • Adult Stomach Cancer

  • Adult Stomach Carcinoma

  • GASC

  • Gastric Cancer Intestinal

  • Gastric Cancers

  • Gastric Carcinomas

  • Cancer, Gastric

  • Stomach Neoplasm

  • Malignant Neoplasm Of Body Of Stomach

  • Malignant Tumor Of Lesser Curve Of Stomach

  • Gastrocarcinoma Of Unspecified Site

  • Leather Bottle Stomach

  • Carcinoma Of Fundus Of Stomach

  • Cancer Of Fundus Of Stomach

  • Primary Malignant Neoplasm Of Body Of Stomach

  • Cancer Of Body Of Stomach

  • Primary Malignant Neoplasm Of Pyloric Antrum

  • Pyloric Antrum Cancer

  • Malignant Tumour Of Stomach
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (3)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS04344 EMCN Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS20274 Emcn Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS26782 Emcn Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Bos taurus EMCN VGNC VGNC:53710
Canis familiaris EMCN VGNC VGNC:40339
Mus musculus EMCN MGD MGI:1891716
Macaca mulatta EMCN VGNC VGNC:100223
Rattus norvegicus EMCN RGD RGD:1303218
Felis catus EMCN VGNC VGNC:61839
Others EMCN NCBI