PHAX - phosphorylated adaptor for RNA export Gene

Also Known as RNUXA

生物種: Homo sapiens

遺伝子タイプ: protein coding
遺伝子ID: 51808

About PHAX

Cytogenetic location: 5q23.2 Genomic coordinates (GRCh38): 5:126,600,947-126,627,252 (from NCBI)

This gene has 5 transcripts (splice variants) and 205 orthologues. Ubiquitous expression in brain (RPKM 11.7), endometrium (RPKM 7.4) and 25 other tissues.

Summary

Enables mRNA cap binding complex binding activity. Involved in RNA stabilization. Located in centrosome and nucleoplasm. Part of ribonucleoprotein complex. [provided by Alliance of Genome Resources, Apr 2022]

PHAX Products (1)

mRNA Protein Name
NM_032177.4 NP_115553.2 phosphorylated adapter RNA export protein

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence 参考文献 由来
enables mRNA cap binding complex binding IDA
IDA: Inferred from direct assay
28297668 GOA
enables protein binding IPI
IPI: Inferred from physical interaction
26382858 GOA
Biological Process GO Annotation Evidence 参考文献 由来
involved in RNA stabilization IMP
IMP: Inferred from mutant phenotype
28297668 GOA
Cellular Component GO Annotation Evidence 参考文献 由来
part of ribonucleoprotein complex IDA
IDA: Inferred from direct assay
28297668 GOA
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

PHAX Protein Structure

RNA_GG_bind

RNA_GG_bind: PHAX RNA-binding domain (229 - 315)

  • 0
  • 100
  • 200
  • 300
  • 394 a.a.
Protein Preferred Names Protein Names

phosphorylated adapter RNA export protein

  • RNA U small nuclear RNA export adapter protein

関連疾患

Diseases Alias
Leukodystrophy, Demyelinating, Adult-Onset, Autosomal Dominant

  • ADLD

  • Adult-Onset Autosomal Dominant Demyelinating Leukodystrophy

  • Leukodystrophy, Adult-Onset, Autosomal Dominant

  • Adult-Onset Autosomal Dominant Leukodystrophy

  • Autosomal Dominant Leukodystrophy With Autonomic Disease

  • Autosomal Dominant Adult-Onset Demyelinating Leukodystrophy

  • Multiple Sclerosis-Like Disorder

  • Pelizaeus-Merzbacher Disease, Autosomal Dominant Or Late-Onset Type, Formerly

  • Autosomal-Dominant Or Late-Onset Type Pelizaeus-Merzbacher Disease

  • Pelizaeus-Merzbacher Disease, Autosomal Dominant Or Late-Onset Type

  • Adult-Onset Autosomal Dominant Leukodystrophy With Autonomic Symptoms

  • Lmnb1-Related Adult-Onset Autosomal Dominant Leukodystrophy

  • Leukodystrophy, Demyelinating, Autosomal Dominant, Adult-Onset

  • Pelizaeus-Merzbacher Disease Autosomal Dominant

  • Pelizaeus-Merzbacher Disease Late-Onset Type

  • Adult Onset Autosomal Dominant Leukodystrophy
Retinitis Pigmentosa 57

  • RP57

  • Pde6g-Related Retinitis Pigmentosa

  • Retinitis Pigmentosa, Type 57
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
製品番号 製品名
製品効果
純度
Rare Diseases
HY-RS10406 PHAX Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

生物種 Symbol 由来 ID
Mus musculus PHAX MGD MGI:1891839
Macaca mulatta PHAX VGNC VGNC:97805
Felis catus PHAX VGNC VGNC:64131
Rattus norvegicus PHAX RGD RGD:708448
Bos taurus PHAX VGNC VGNC:32807
Canis familiaris PHAX VGNC VGNC:51915
Others PHAX NCBI