Tmem38b - transmembrane protein 38B Gene

Also Known as mg33b; TRIC-B; D4Ertd89e; 1600017F22Rik

Species: Mus musculus

Gene Type: protein coding
Gene ID: 52076

Summary

Predicted to enable Potassium Channel activity. Acts upstream of or within several processes, including cellular response to caffeine; lung development; and regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion. Located in endoplasmic reticulum. Human ortholog(s) of this gene implicated in osteogenesis imperfecta type 14. Orthologous to human TMEM38B (transmembrane protein 38B). [provided by Alliance of Genome Resources, Apr 2022]

Tmem38b Products (1)

mRNA Protein Name
NM_028053.2 NP_082329.1 trimeric intracellular cation channel type B

Gene Ontology

  • Biological Process
  • Cellular Component
Biological Process GO Annotation Evidence References Source
acts upstream of or within bone development IMP
IMP: Inferred from mutant phenotype
27188440 MGI
acts upstream of or within bone mineralization IMP
IMP: Inferred from mutant phenotype
27188440 MGI
acts upstream of or within cellular response to caffeine IGI
IGI: Inferred from genetic interaction
17611541 MGI
acts upstream of or within endoplasmic reticulum organization IGI
IGI: Inferred from genetic interaction
17611541 MGI
acts upstream of or within endoplasmic reticulum organization IMP
IMP: Inferred from mutant phenotype
27188440 MGI
acts upstream of or within establishment of localization in cell IMP
IMP: Inferred from mutant phenotype
19515693 MGI
acts upstream of or within extracellular matrix constituent secretion IMP
IMP: Inferred from mutant phenotype
27188440 MGI
acts upstream of or within lung alveolus development IMP
IMP: Inferred from mutant phenotype
19515693 MGI
acts upstream of or within lung epithelial cell differentiation IMP
IMP: Inferred from mutant phenotype
19515693 MGI
acts upstream of or within ossification IMP
IMP: Inferred from mutant phenotype
27188440 MGI
acts upstream of or within phospholipid biosynthetic process IMP
IMP: Inferred from mutant phenotype
19515693 MGI
acts upstream of or within regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion IGI
IGI: Inferred from genetic interaction
17611541 MGI
acts upstream of or within release of sequestered calcium ion into cytosol IMP
IMP: Inferred from mutant phenotype
19515693 MGI
acts upstream of or within release of sequestered calcium ion into cytosol by endoplasmic reticulum IMP
IMP: Inferred from mutant phenotype
27188440 MGI
acts upstream of or within release of sequestered calcium ion into cytosol by sarcoplasmic reticulum IGI
IGI: Inferred from genetic interaction
17611541 MGI
acts upstream of or within secretion by lung epithelial cell involved in lung growth IMP
IMP: Inferred from mutant phenotype
19515693 MGI
Cellular Component GO Annotation Evidence References Source
located in endoplasmic reticulum membrane IDA
IDA: Inferred from direct assay
17611541 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

trimeric intracellular cation channel type B

  • Mitsugumin33B

  • TRICB

  • mitsugumin-33B

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS14720 TMEM38B Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Tmem38b NCBI NCBI:55151