Ube2k - ubiquitin-conjugating enzyme E2K Gene

Also Known as Lig; Hip2; Hypg; HIP-2; E2-25k; D5Ertd601e

Species: Mus musculus

Gene Type: protein coding
Gene ID: 53323

Summary

Predicted to enable ubiquitin conjugating enzyme activity; ubiquitin protein Ligase binding activity; and ubiquitin-ubiquitin Ligase activity. Acts upstream of or within regulation of proteasomal ubiquitin-dependent protein catabolic process. Located in cytoplasm; filopodium tip; and nucleus. Is expressed in several structures, including alimentary system; brain; genitourinary system; respiratory system; and sensory organ. Orthologous to human UBE2K (ubiquitin conjugating enzyme E2 K). [provided by Alliance of Genome Resources, Apr 2022]

Ube2k Products (3)

mRNA Protein Name
NM_001310618.1 NP_001297547.1 ubiquitin-conjugating enzyme E2 K isoform 2
NM_001310619.1 NP_001297548.1 ubiquitin-conjugating enzyme E2 K isoform 3
NM_016786.4 NP_058066.2 ubiquitin-conjugating enzyme E2 K isoform 1

Gene Ontology

  • Biological Process
  • Cellular Component
Biological Process GO Annotation Evidence References Source
acts upstream of or within regulation of proteasomal ubiquitin-dependent protein catabolic process IDA
IDA: Inferred from direct assay
18710920 MGI
Cellular Component GO Annotation Evidence References Source
located in cytoplasm IDA
IDA: Inferred from direct assay
18511602 MGI
located in filopodium tip IDA
IDA: Inferred from direct assay
18511602 MGI
located in nucleus IDA
IDA: Inferred from direct assay
18511602 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

ubiquitin-conjugating enzyme E2 K

  • E2 ubiquitin-conjugating enzyme K

  • huntingtin interacting protein 2

  • ubiquitin carrier protein

  • ubiquitin-conjugating enzyme E2-25 kDa

  • ubiquitin-conjugating enzyme E2K (UBC1 homolog, yeast)

  • ubiquitin-protein ligase

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (3)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS15352 UBE2K Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS19042 Ube2k Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS25532 Ube2k Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Ube2k NCBI NCBI:3093