Atoh7 - atonal bHLH transcription factor 7 Gene

Also Known as Math5; bHLHa13

Species: Mus musculus

Gene Type: protein coding
Gene ID: 53404

Summary

Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Involved in entrainment of circadian clock by photoperiod. Acts upstream of or within circadian rhythm; entrainment of circadian clock; and neural retina development. Predicted to be active in nucleus. Is expressed in several structures, including central nervous system; dorsal root ganglion; early conceptus; eye; and genitourinary system. Human ortholog(s) of this gene implicated in persistent hyperplastic primary vitreous. Orthologous to human ATOH7 (atonal bHLH transcription factor 7). [provided by Alliance of Genome Resources, Apr 2022]

Atoh7 Products (2)

mRNA Protein Name
NM_001364648.2 NP_001351577.1 transcription factor Atoh7 isoform 2
NM_016864.3 NP_058560.1 transcription factor Atoh7 isoform 1

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables transcription cis-regulatory region binding IDA
IDA: Inferred from direct assay
33712461 MGI
Biological Process GO Annotation Evidence References Source
acts upstream of or within circadian rhythm IMP
IMP: Inferred from mutant phenotype
12451142 MGI
acts upstream of or within entrainment of circadian clock IMP
IMP: Inferred from mutant phenotype
12451142 MGI
involved in entrainment of circadian clock by photoperiod IMP
IMP: Inferred from mutant phenotype
26392540 MGI
acts upstream of or within neural retina development IMP
IMP: Inferred from mutant phenotype
21441919 MGI
involved in positive regulation of retinal ganglion cell axon guidance IMP
IMP: Inferred from mutant phenotype
33712461 MGI
involved in regulation of transcription by RNA polymerase II IMP
IMP: Inferred from mutant phenotype
33712461 MGI
involved in response to auditory stimulus IMP
IMP: Inferred from mutant phenotype
17977745 MGI
Cellular Component GO Annotation Evidence References Source
located in axon IDA
IDA: Inferred from direct assay
17977745 MGI
located in nucleus IMP
IMP: Inferred from mutant phenotype
33712461 MGI
located in perikaryon IDA
IDA: Inferred from direct assay
17977745 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

transcription factor Atoh7

  • helix-loop-helix protein mATH-5

  • protein atonal homolog 7

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS01166 ATOH7 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Atoh7 NCBI NCBI:220202