Ybx2 - Y box protein 2 Gene

Mus musculus

Also known as Msy2

Gene ID: 53422 | Gene type: protein coding

About Ybx2

Summary

Enables several functions, including chromatin binding activity; mRNA 3'-UTR binding activity; and ribonucleoprotein complex binding activity. Involved in positive regulation of cold-induced thermogenesis. Acts upstream of or within germ cell development; negative regulation of binding activity; and posttranscriptional regulation of gene expression. Located in cytoplasm. Part of polysome. Is expressed in early conceptus; eye; gonad; and trunk somite. Orthologous to human YBX2 (Y-box binding protein 2). [provided by Alliance of Genome Resources, Apr 2022]

Ybx2 Products(3)

mRNA	Protein	Name
NM_001347634.3	NP_001334563.1	Y-box-binding protein 2 isoform 2
NM_001404612.1	NP_001391541.1	Y-box-binding protein 2 isoform 3
NM_016875.4	NP_058571.2	Y-box-binding protein 2 isoform 1

Gene Ontology

Molecular Function
Biological Process
Cellular Component

Molecular Function GO Annotation	Evidence	Reference	Source
enables chromatin binding	IDA IDA: Inferred from direct assay	15665108	MGI
enables lipid binding	IDA IDA: Inferred from direct assay	15665108	MGI
enables mRNA 3'-UTR binding	IDA IDA: Inferred from direct assay	10772793	MGI
enables mRNA binding	IDA IDA: Inferred from direct assay	12297523	MGI
enables ribonucleoprotein complex binding	IDA IDA: Inferred from direct assay	17035640	MGI
enables translation regulator activity	IDA IDA: Inferred from direct assay	12297523	MGI

Biological Process GO Annotation	Evidence	Reference	Source
acts upstream of or within mRNA stabilization	IMP IMP: Inferred from mutant phenotype	17035640	MGI
acts upstream of or within negative regulation of binding	IMP IMP: Inferred from mutant phenotype	17035640	MGI
acts upstream of or within negative regulation of translation	IDA IDA: Inferred from direct assay	15665108	MGI
acts upstream of or within oogenesis	IMP IMP: Inferred from mutant phenotype	15824319	MGI
involved in positive regulation of cold-induced thermogenesis	IMP IMP: Inferred from mutant phenotype	28970281	MGI
acts upstream of or within spermatid development	IMP IMP: Inferred from mutant phenotype	15824319	MGI

Cellular Component GO Annotation	Evidence	Reference	Source
located in cytoplasm	IDA IDA: Inferred from direct assay	11566752	MGI
part of ribonucleoprotein complex	IDA IDA: Inferred from direct assay	15665108	MGI

EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

Protein Preferred Names

Protein Names

Y-box-binding protein 2

Y-box protein MSY2

germ cell-specific Y-box-binding protein

Related Agents

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS15917	YBX2 Human Pre-designed siRNA Set A	Pre-designed Set	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Homo sapiens	Ybx2	NCBI	NCBI:51087

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