Ybx2 - Y box protein 2 Gene

Also Known as Msy2

Species: Mus musculus

Gene Type: protein coding
Gene ID: 53422

Summary

Enables several functions, including chromatin binding activity; mRNA 3'-UTR binding activity; and ribonucleoprotein complex binding activity. Involved in positive regulation of cold-induced thermogenesis. Acts upstream of or within germ cell development; negative regulation of binding activity; and posttranscriptional regulation of gene expression. Located in cytoplasm. Part of polysome. Is expressed in early conceptus; eye; gonad; and trunk somite. Orthologous to human YBX2 (Y-box binding protein 2). [provided by Alliance of Genome Resources, Apr 2022]

Ybx2 Products (3)

mRNA Protein Name
NM_001347634.3 NP_001334563.1 Y-box-binding protein 2 isoform 2
NM_001404612.1 NP_001391541.1 Y-box-binding protein 2 isoform 3
NM_016875.4 NP_058571.2 Y-box-binding protein 2 isoform 1

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables chromatin binding IDA
IDA: Inferred from direct assay
15665108 MGI
enables lipid binding IDA
IDA: Inferred from direct assay
15665108 MGI
enables mRNA 3'-UTR binding IDA
IDA: Inferred from direct assay
10772793 MGI
enables mRNA binding IDA
IDA: Inferred from direct assay
12297523 MGI
enables ribonucleoprotein complex binding IDA
IDA: Inferred from direct assay
17035640 MGI
enables translation regulator activity IDA
IDA: Inferred from direct assay
12297523 MGI
Biological Process GO Annotation Evidence References Source
acts upstream of or within mRNA stabilization IMP
IMP: Inferred from mutant phenotype
17035640 MGI
acts upstream of or within negative regulation of binding IMP
IMP: Inferred from mutant phenotype
17035640 MGI
acts upstream of or within negative regulation of translation IDA
IDA: Inferred from direct assay
15665108 MGI
acts upstream of or within oogenesis IMP
IMP: Inferred from mutant phenotype
15824319 MGI
involved in positive regulation of cold-induced thermogenesis IMP
IMP: Inferred from mutant phenotype
28970281 MGI
acts upstream of or within spermatid development IMP
IMP: Inferred from mutant phenotype
15824319 MGI
Cellular Component GO Annotation Evidence References Source
located in cytoplasm IDA
IDA: Inferred from direct assay
11566752 MGI
part of ribonucleoprotein complex IDA
IDA: Inferred from direct assay
15665108 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

Y-box-binding protein 2

  • Y-box protein MSY2

  • germ cell-specific Y-box-binding protein

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS15917 YBX2 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Ybx2 NCBI NCBI:51087