2. Gene
  3. RORA - RAR related orphan receptor A Gene

RORA - RAR related orphan receptor A Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Bos taurus
Gene ID: 535597 | Gene type: protein coding

About RORA

Primary_assembly 10: 48,892,525-49,702,163 forward strand.ARS-UCD1.2:CM008177.2

This gene has 3 transcripts (splice variants), 395 orthologues and 18 paralogues.

Summary

The protein encoded by this gene is a member of the NR1 subfamily of nuclear hormone receptors. It can bind as a monomer or as a homodimer to hormone response elements upstream of several genes to enhance the expression of those genes. The encoded protein has been shown to interact with NM23-2, a nucleoside diphosphate kinase involved in organogenesis and differentiation, as well as with NM23-1, the product of a tumor metastasis suppressor candidate gene. Also, it has been shown to aid in the transcriptional regulation of some genes involved in circadian rhythm. [provided by RefSeq, Feb 2014]

RORA Products(1)

mRNA Protein Name
NM_001192861.1 NP_001179790.1 nuclear receptor ROR-alpha

RORA Protein Structure

NR_DBD_ROR

NR_DBD_ROR: cd06968 (65 - 159)

NR_LBD_ROR_like

NR_LBD_ROR_like: cd06939 (271 - 510)

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  • 523 a.a.
Protein Preferred Names Protein Names

nuclear receptor ROR-alpha

Related Agents

Pre-clinical Phase
Bioactive Molecules (3)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS12126 RORA Human Pre-designed siRNA Set A / Unkown
HY-RS12127 Rora Mouse Pre-designed siRNA Set A / Unkown
HY-RS12128 RORA Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens RORA NCBI NCBI:6095