Llgl1 - LLGL scribble cell polarity complex component 1 Gene

Also Known as LLGL; Mgl1; Rgl1; Llglh; Rgl-1

Species: Rattus norvegicus

Gene Type: protein coding
Gene ID: 54265

Summary

Enables GTPase activator activity and small GTPase binding activity. Involved in Golgi to plasma membrane transport and axonogenesis. Located in Golgi cis cisterna; early endosome membrane; and trans-Golgi network membrane. Colocalizes with axon. Orthologous to human LLGL1 (LLGL scribble cell polarity complex component 1). [provided by Alliance of Genome Resources, Apr 2022]

Llgl1 Products (1)

mRNA Protein Name
NM_001304613.1 NP_001291542.1 lethal(2) giant larvae protein homolog 1

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables GTPase activator activity IDA
IDA: Inferred from direct assay
21856246 RGD
enables small GTPase binding IPI
IPI: Inferred from physical interaction
21856246 RGD
Biological Process GO Annotation Evidence References Source
involved in Golgi to plasma membrane transport IMP
IMP: Inferred from mutant phenotype
21856246 RGD
involved in axonogenesis IMP
IMP: Inferred from mutant phenotype
21856246 RGD
Cellular Component GO Annotation Evidence References Source
located in Golgi cis cisterna IDA
IDA: Inferred from direct assay
21856246 RGD
located in axon IDA
IDA: Inferred from direct assay
21856246 RGD
located in early endosome membrane IDA
IDA: Inferred from direct assay
21856246 RGD
located in trans-Golgi network membrane IDA
IDA: Inferred from direct assay
21856246 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

lethal(2) giant larvae protein homolog 1

  • LLGL1, scribble cell polarity complex component

  • lethal giant larvae homolog 1, scribble cell polarity complex component

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS07700 LLGL1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Llgl1 NCBI NCBI:3996