Irx5 - Iroquois homeobox 5 Gene

Species: Mus musculus

Gene Type: protein coding
Gene ID: 54352

Summary

Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Acts upstream of or within neuron differentiation; regulation of gene expression; and regulation of heart rate. Predicted to be active in nucleus. Is expressed in several structures, including alimentary system; central nervous system; heart; limb; and sensory organ. Orthologous to human IRX5 (iroquois homeobox 5). [provided by Alliance of Genome Resources, Apr 2022]

Irx5 Products (1)

mRNA Protein Name
NM_018826.2 NP_061296.1 iroquois-class homeodomain protein IRX-5

Gene Ontology

  • Biological Process
Biological Process GO Annotation Evidence References Source
acts upstream of or within cell development IMP
IMP: Inferred from mutant phenotype
16182275 MGI
acts upstream of or within neuron maturation IGI
IGI: Inferred from genetic interaction
18322081 MGI
acts upstream of or within regulation of gene expression IMP
IMP: Inferred from mutant phenotype
16239150 MGI
acts upstream of or within regulation of heart rate IMP
IMP: Inferred from mutant phenotype
16239150 MGI
acts upstream of or within retinal bipolar neuron differentiation IGI
IGI: Inferred from genetic interaction
18322081 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

iroquois-class homeodomain protein IRX-5

  • homeodomain protein IRXB2

  • iroquois homeobox protein 5

  • iroquois related homeobox 5

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (2)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS06920 IRX1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS06924 IRX5 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Irx5 NCBI NCBI:10265