Hpse2 - heparanase 2 Gene

Also Known as Hpa2; Gm968

Species: Mus musculus

Gene Type: protein coding
Gene ID: 545291

Summary

Predicted to enable heparan sulfate proteoglycan binding activity. Acts upstream of or within extracellular matrix organization and positive regulation of cell population proliferation. Predicted to be located in extracellular region and membrane. Predicted to be active in extracellular matrix. Is expressed in bladder; brain; metanephros; and ureter. Used to study urofacial syndrome. Human ortholog(s) of this gene implicated in urofacial syndrome. Orthologous to human HPSE2 (heparanase 2 (inactive)). [provided by Alliance of Genome Resources, Apr 2022]

Hpse2 Products (1)

mRNA Protein Name
NM_001081257.2 NP_001074726.1 inactive heparanase-2 precursor

Gene Ontology

  • Biological Process
Biological Process GO Annotation Evidence References Source
acts upstream of cell population proliferation IMP
IMP: Inferred from mutant phenotype
25510506 MGI
acts upstream of or within extracellular matrix organization IMP
IMP: Inferred from mutant phenotype
25510506 MGI
acts upstream of or within positive regulation of cell population proliferation IMP
IMP: Inferred from mutant phenotype
25510506 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

inactive heparanase-2

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS06351 HPSE2 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Hpse2 NCBI NCBI:60495