Cfhr2 - complement factor H-related 2 Gene
Also Known as FHR-B; Cfhrb_4/2
Species: Mus musculus
Gene Type: protein coding
Gene ID: 545366
Summary
Enables complement component C3b binding activity and heparin binding activity. Predicted to be involved in regulation of complement activation. Located in extracellular space. Human ortholog(s) of this gene implicated in age related macular degeneration 1 and atypical hemolytic-uremic syndrome. Orthologous to several human genes including CFHR3 (Complement Factor H Related 3). [provided by Alliance of Genome Resources, Apr 2022]
Cfhr2 Products (1)
| mRNA | Protein | Name |
|---|---|---|
| NM_001025575.2 | NP_001020746.1 | complement factor H-related protein B precursor |
| Molecular Function GO Annotation | Evidence | References | Source |
|---|---|---|---|
| enables complement component C3b binding |
IPI
IPI: Inferred from physical interaction
|
17028856 | MGI |
| enables heparin binding |
IDA
IDA: Inferred from direct assay
|
17028856 | MGI |
| Cellular Component GO Annotation | Evidence | References | Source |
|---|---|---|---|
| located in extracellular space |
IDA
IDA: Inferred from direct assay
|
17028856 | MGI |
EXP: Inferred from Experiment
IDA: Inferred from direct assay
IPI: Inferred from physical interaction
IMP: Inferred from mutant phenotype
IGI: Inferred from genetic interaction
IEP: Inferred from expression pattern
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| Protein Preferred Names | Protein Names | |
|---|---|---|
|
complement factor H-related protein B |
|