Scrt2 - scratch family zinc finger 2 Gene

Species: Mus musculus

Gene Type: protein coding
Gene ID: 545474

Summary

Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Acts upstream of or within negative regulation of transcription by RNA polymerase II and regulation of neuron migration. Located in nucleus. Is expressed in future hindbrain; nervous system; and retina. Orthologous to human SCRT2 (scratch family transcriptional repressor 2). [provided by Alliance of Genome Resources, Apr 2022]

Scrt2 Products (1)

mRNA Protein Name
NM_001160410.2 NP_001153882.1 transcriptional repressor scratch 2
Biological Process GO Annotation Evidence References Source
acts upstream of or within negative regulation of transcription by RNA polymerase II IDA
IDA: Inferred from direct assay
23434913 MGI
acts upstream of or within regulation of neuron migration IMP
IMP: Inferred from mutant phenotype
23434913 MGI
Cellular Component GO Annotation Evidence References Source
located in nucleus IDA
IDA: Inferred from direct assay
23434913 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

transcriptional repressor scratch 2

  • ortholog of human scratch homolog 2, zinc finger protein SCRT2

  • scratch homolog 2, zinc finger protein

Orthologs Information

Species Symbol Source ID
Homo sapiens Scrt2 NCBI NCBI:85508