Tubb1 - tubulin, beta 1 class VI Gene

Also Known as M(beta)1; 2810484G07Rik

Species: Mus musculus

Gene Type: protein coding
Gene ID: 545486

Summary

A structural constituent of Cytoskeleton. Acts upstream of or within spindle assembly. Located in microtubule. Is expressed in dorsal root ganglion; liver; and spinal cord. Human ortholog(s) of this gene implicated in autosomal dominant macrothrombocytopenia TUBB1-related. Orthologous to human TUBB1 (tubulin beta 1 class VI). [provided by Alliance of Genome Resources, Apr 2022]

Tubb1 Products (2)

mRNA Protein Name
NM_001080971.2 NP_001074440.1 tubulin beta-1 chain
NM_001080971.2 NP_001074440.1 tubulin beta-1 chain

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables structural constituent of cytoskeleton IDA
IDA: Inferred from direct assay
15121885 MGI
Biological Process GO Annotation Evidence References Source
involved in microtubule polymerization IMP
IMP: Inferred from mutant phenotype
30446499 MGI
acts upstream of or within microtubule-based process IDA
IDA: Inferred from direct assay
15121885 MGI
involved in platelet aggregation IMP
IMP: Inferred from mutant phenotype
30446499 MGI
involved in platelet formation IMP
IMP: Inferred from mutant phenotype
30446499 MGI
acts upstream of or within spindle assembly IDA
IDA: Inferred from direct assay
15121885 MGI
involved in thyroid gland development IMP
IMP: Inferred from mutant phenotype
30446499 MGI
involved in thyroid hormone transport IMP
IMP: Inferred from mutant phenotype
30446499 MGI
Cellular Component GO Annotation Evidence References Source
located in microtubule IDA
IDA: Inferred from direct assay
18347012 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

tubulin beta-1 chain

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (4)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-115715 EN219 99.21% Unkown
HY-115715A EN219-alkyne 99.62% Unkown
HY-RS15250 TUBB Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS15251 TUBB1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Tubb1 NCBI NCBI:81027