EQTN - equatorin Gene

Homo sapiens

Also known as AFAF; SPACA8; C9orf11

Gene ID: 54586 | Gene type: protein coding

About EQTN

Cytogenetic location: 9p21.2 Genomic coordinates (GRCh38): 9:27,284,654-27,297,150 (from NCBI)

This gene has 4 transcripts (splice variants) and 62 orthologues. Restricted expression toward testis (RPKM 7.3).

Summary

Predicted to be involved in acrosomal vesicle exocytosis; endocytosis; and fusion of sperm to egg plasma membrane involved in single fertilization. Predicted to be located in acrosomal membrane; early endosome; and nucleus. Predicted to be active in inner acrosomal membrane; outer acrosomal membrane; and plasma membrane. [provided by Alliance of Genome Resources, Apr 2022]

EQTN Products(2)

mRNA	Protein	Name
NM_001161585.2	NP_001155057.1	equatorin isoform 2 precursor
NM_020641.3	NP_065692.2	equatorin isoform 1 precursor

EQTN Protein Structure

Afaf

0
100
200
294 a.a.

Protein Preferred Names

Protein Names

equatorin

Acrosome formation associated factor

Related Diseases

Diseases

Alias

Bronchiectasis 1

Tumoral Calcinosis, Hyperphosphatemic, Familial, 1

Hyperphosphatemic Familial Tumoral Calcinosis	Hftc
Hyperostosis-Hyperphosphatemia Syndrome	Familial Hyperphosphatemic Tumoral Calcinosis/Hyperphosphatemic Hyperostosis Syndrome
Tumoral Calcinosis, Hyperphosphatemic, Familial	Phptc
Lipocalcinogranulomatosis	Morbus Teutschlaender
Hhs	Hyperostosis With Hyperphosphatemia
Cortical Hyperostosis With Hyperphosphatemia	Primary Hyperphosphatemic Tumoral Calcinosis
Familial Tumoral Calcinosis	HFTC1
Hypercalcemic Tumoral Calcinosis	Hyperphosphatemia Hyperostosis
Hyperphosphatemia Hyperostosis Syndrome	Hyperphosphatemia Tumoral Calcinosis
Tumoral Calcinosis	Calcinosis, Tumoral, With Hyperphosphatemia
Tumoral Calcinosis, Primary Hyperphosphatemic	Teutschlaender Disease, Familial
Familial Teutschlaender Disease	Tumoral Calcinosis With Hyperphosphatemia
Familial Tumoral Calcinosis/Hyperostosis-Hyperphosphatemia Syndrome	Ftc/Hhs
Familial Tumoral Calcinosis With Hyperphosphatemia	Teutschlaender Disease
Tumoral Calcinosis Primary Hyperphosphatemic	Calcinosis, Tumoral, Hyperphosphatemic, Familial

Diseases	Alias
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS04461	EQTN Human Pre-designed siRNA Set A		/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Felis catus	EQTN	VGNC	VGNC:102923
Mus musculus	EQTN	MGD	MGI:1915003
Bos taurus	EQTN	VGNC	VGNC:56963
Canis familiaris	EQTN	VGNC	VGNC:51714
Macaca mulatta	EQTN	VGNC	VGNC:72040
Rattus norvegicus	EQTN	RGD	RGD:1563332