2. Gene
  3. Wdr45 - WD repeat domain 45 Gene

Wdr45 - WD repeat domain 45 Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Mus musculus

Also known as JM5; Sfc19; Wdrx1; WIPI-4; DXImx38e

Gene ID: 54636 | Gene type: protein coding

About Wdr45

Summary

Predicted to enable phosphatidylinositol-3,5-bisphosphate binding activity; phosphatidylinositol-3-phosphate binding activity; and protein kinase binding activity. Predicted to be involved in several processes, including Autophagy of mitochondrion; Autophagy of nucleus; and protein localization to phagophore assembly site. Predicted to be located in phagophore assembly site. Predicted to be active in cytosol and phagophore assembly site membrane. Predicted to be extrinsic component of membrane. Is expressed in 2-cell stage embryo; 4-cell stage embryo; and lung. Used to study neurodegeneration with brain iron accumulation 5. Human ortholog(s) of this gene implicated in neurodegeneration with brain iron accumulation 5. Orthologous to human WDR45 (WD repeat domain 45). [provided by Alliance of Genome Resources, Apr 2022]

Wdr45 Products(4)

mRNA Protein Name
NM_001290792.1 NP_001277721.1 WD repeat domain phosphoinositide-interacting protein 4 isoform a
NM_001290794.1 NP_001277723.1 WD repeat domain phosphoinositide-interacting protein 4 isoform a
NM_001290795.1 NP_001277724.1 WD repeat domain phosphoinositide-interacting protein 4 isoform b
NM_172372.2 NP_758960.1 WD repeat domain phosphoinositide-interacting protein 4 isoform a
Protein Preferred Names Protein Names

WD repeat domain phosphoinositide-interacting protein 4

WD repeat domain, X-linked 1

WD repeat-containing protein 45

Related Agents

Pre-clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS15781 WDR45 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Wdr45 NCBI NCBI:11152