Cacna1f - calcium channel, voltage-dependent, alpha 1F subunit Gene

Also Known as nob2; Sfc17; nerg1; Cav1.4; A930034B14

Species: Mus musculus

Gene Type: protein coding
Gene ID: 54652

Summary

Enables voltage-gated Calcium Channel activity. Acts upstream of or within several processes, including neuron projection morphogenesis; retina development in camera-type eye; and visual perception. Predicted to be located in membrane and neuronal cell body. Predicted to be integral component of membrane. Predicted to be part of voltage-gated Calcium Channel complex. Used to study congenital stationary night blindness 2A. Human ortholog(s) of this gene implicated in Aland Island eye disease; X-linked cone-rod dystrophy 3; congenital stationary night blindness; and congenital stationary night blindness 2A. Orthologous to human CACNA1F (calcium voltage-gated channel subunit alpha1 F). [provided by Alliance of Genome Resources, Apr 2022]

Cacna1f Products (1)

mRNA Protein Name
NM_019582.2 NP_062528.2 voltage-dependent L-type calcium channel subunit alpha-1F

Gene Ontology

  • Molecular Function
  • Biological Process
Molecular Function GO Annotation Evidence References Source
enables voltage-gated calcium channel activity IMP
IMP: Inferred from mutant phenotype
16155113 MGI
Biological Process GO Annotation Evidence References Source
acts upstream of or within axonogenesis IMP
IMP: Inferred from mutant phenotype
16155113 MGI
acts upstream of or within dendrite morphogenesis IMP
IMP: Inferred from mutant phenotype
16155113 MGI
acts upstream of or within intracellular calcium ion homeostasis IMP
IMP: Inferred from mutant phenotype
16155113 MGI
acts upstream of or within retina development in camera-type eye IMP
IMP: Inferred from mutant phenotype
21052544 MGI
acts upstream of or within visual perception IMP
IMP: Inferred from mutant phenotype
16155113 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

voltage-dependent L-type calcium channel subunit alpha-1F

  • L-type dihydropyridine-sensitive calcium channel alpha-1f subunit

  • voltage-gated calcium channel subunit alpha Cav1.4

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS01796 CACNA1F Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Cacna1f NCBI NCBI:778