2. Gene
  3. PIGX - phosphatidylinositol glycan anchor biosynthesis class X Gene

PIGX - phosphatidylinositol glycan anchor biosynthesis class X Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Homo sapiens

Also known as PIG-X

Gene ID: 54965 | Gene type: protein coding

About PIGX

Cytogenetic location: 3q29 Genomic coordinates (GRCh38): 3:196,712,377-196,736,007 (from NCBI)

This gene has 9 transcripts (splice variants) and 192 orthologues. Ubiquitous expression in brain (RPKM 7.7), prostate (RPKM 7.3) and 25 other tissues.

Summary

This gene encodes a type I transmembrane protein in the endoplasmic reticulum (ER). The protein is an essential component of glycosylphosphatidylinositol-mannosyltransferase I, which transfers the first of the four mannoses in the GPI-anchor precursors during GPI-anchor biosynthesis. Studies in rat indicate that the protein is translated from a non-AUG translation initiation site. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Oct 2009]

PIGX Products(2)

mRNA Protein Name
NM_001166304.2 NP_001159776.1 phosphatidylinositol-glycan biosynthesis class X protein isoform 1 precursor
NM_017861.4 NP_060331.3 phosphatidylinositol-glycan biosynthesis class X protein isoform 2 precursor

PIGX Protein Structure

PIG-X

PIG-X: PIG-X / PBN1 (54 - 252)

  • 0
  • 100
  • 200
  • 258 a.a.
Protein Preferred Names Protein Names

phosphatidylinositol-glycan biosynthesis class X protein

GPI-mannosyltransferase subunit

Related Agents

Pre-clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS10506 PIGX Human Pre-designed siRNA Set A / Unkown

Orthologs Information

Species Symbol Source ID
Rattus norvegicus PIGX RGD RGD:1307289
Macaca mulatta PIGX VGNC VGNC:75867
Canis familiaris PIGX VGNC VGNC:44546
Felis catus PIGX VGNC VGNC:64172
Mus musculus PIGX MGD MGI:1919334
Bos taurus PIGX VGNC VGNC:53598