2. Gene
  3. SUSD4 - sushi domain containing 4 Gene

SUSD4 - sushi domain containing 4 Gene

  • Gene
  • Protein
  • Disease
  • Agent
  • Ortholog
Homo sapiens

Also known as PRO222

Gene ID: 55061 | Gene type: protein coding

About SUSD4

Cytogenetic location: 1q41 Genomic coordinates (GRCh38): 1:223,220,831-223,365,235 (from NCBI)

This gene has 17 transcripts (splice variants), 145 orthologues and 39 paralogues. Biased expression in esophagus (RPKM 11.1), ovary (RPKM 10.5) and 13 other tissues.

Summary

Involved in negative regulation of complement activation, alternative pathway and negative regulation of complement activation, classical pathway. Predicted to be located in extracellular region. Predicted to be integral component of membrane. [provided by Alliance of Genome Resources, Apr 2022]

SUSD4 Products(3)

mRNA Protein Name
NM_001037175.3 NP_001032252.1 sushi domain-containing protein 4 isoform b precursor
NM_001410929.1 NP_001397858.1 sushi domain-containing protein 4 isoform c
NM_017982.4 NP_060452.3 sushi domain-containing protein 4 isoform a precursor

SUSD4 Protein Structure

Sushi

Sushi: Sushi repeat (SCR repeat) (57 - 104)

Sushi

Sushi: Sushi repeat (SCR repeat) (122 - 177)

Sushi

Sushi: Sushi repeat (SCR repeat) (180 - 237)

Sushi

Sushi: Sushi repeat (SCR repeat) (243 - 297)

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  • 490 a.a.
Protein Preferred Names Protein Names

sushi domain-containing protein 4

YHGM196

Recombinant SUSD4 Proteins

Cat. No. Product Name Accession Purity
HY-P77217 SUSD4 Protein, Human (HEK293, Fc) Q5VX71-3 (F42-F290) ≥95%

Related Diseases

Diseases Alias
Chromosome 1q41-Q42 Deletion Syndrome

1q41-Q42 Microdeletion Syndrome

1q41q42 Microdeletion Syndrome

Holoprosencephaly 10, Included

Hpe10, Included

1q41-Q42 Deletion Syndrome

Deletion 1q41-Q42

Monosomy 1q41-Q42

Del(1)(Q41q42)

Monosomy 1q41q42

Chromosome Deletion Syndrome 1q41-Q42

Holoprosencephaly 10
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS14049 SUSD4 Human Pre-designed siRNA Set A / Unkown

Orthologs Information

Species Symbol Source ID
Mus musculus SUSD4 MGD MGI:2138351
Felis catus SUSD4 VGNC VGNC:65855
Bos taurus SUSD4 VGNC VGNC:35489
Canis familiaris SUSD4 VGNC VGNC:49817
Rattus norvegicus SUSD4 RGD RGD:1564043
Macaca mulatta SUSD4 VGNC VGNC:78211
Others SUSD4 NCBI