SLC25A36 - solute carrier family 25 member 36 Gene

Also Known as PNC2

Species: Homo sapiens

Gene Type: protein coding
Gene ID: 55186

About SLC25A36

Cytogenetic location: 3q23 Genomic coordinates (GRCh38): 3:140,941,836-140,980,995 (from NCBI)

This gene has 16 transcripts (splice variants), 298 orthologues and 49 paralogues. Ubiquitous expression in bone marrow (RPKM 19.4), endometrium (RPKM 15.5) and 24 other tissues.

Summary

Enables pyrimidine nucleotide transmembrane transporter activity. Involved in mitochondrial genome maintenance; pyrimidine nucleotide transport; and regulation of mitochondrial membrane potential. Located in mitochondrion. [provided by Alliance of Genome Resources, Apr 2022]

SLC25A36 Products (2)

mRNA Protein Name
NM_001104647.3 NP_001098117.1 solute carrier family 25 member 36 isoform a
NM_018155.3 NP_060625.2 solute carrier family 25 member 36 isoform b

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables pyrimidine nucleotide transmembrane transporter activity IDA
IDA: Inferred from direct assay
25320081 GOA
Biological Process GO Annotation Evidence References Source
involved in mitochondrial genome maintenance IDA
IDA: Inferred from direct assay
25320081 GOA
involved in mitochondrion organization IDA
IDA: Inferred from direct assay
25320081 GOA
involved in pyrimidine nucleotide transport IDA
IDA: Inferred from direct assay
25320081 GOA
involved in regulation of mitochondrial membrane potential IDA
IDA: Inferred from direct assay
25320081 GOA
Cellular Component GO Annotation Evidence References Source
located in mitochondrion IDA
IDA: Inferred from direct assay
25320081 GOA
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

SLC25A36 Protein Structure

Mito_carr

Mito_carr: Mitochondrial carrier protein (5 - 111)

Mito_carr

Mito_carr: Mitochondrial carrier protein (117 - 207)

Mito_carr

Mito_carr: Mitochondrial carrier protein (225 - 309)

  • 0
  • 100
  • 200
  • 311 a.a.
Protein Preferred Names Protein Names

solute carrier family 25 member 36

  • epididymis secretory sperm binding protein

Related Diseases

Diseases Alias
Verrucous Papilloma
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS13118 SLC25A36 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Macaca mulatta SLC25A36 VGNC VGNC:84079
Felis catus SLC25A36 VGNC VGNC:102844
Mus musculus SLC25A36 MGD MGI:1924909
Bos taurus SLC25A36 VGNC VGNC:34762
Rattus norvegicus SLC25A36 RGD RGD:1591928
Canis familiaris SLC25A36 VGNC VGNC:46310
Others SLC25A36 NCBI