GIMAP4 - GTPase, IMAP family member 4 Gene

Also Known as IAN1; IAN-1; IMAP4; MSTP062

Species: Homo sapiens

Gene Type: protein coding
Gene ID: 55303

About GIMAP4

Cytogenetic location: 7q36.1 Genomic coordinates (GRCh38): 7:150,567,390-150,573,953 (from NCBI)

This gene has 5 transcripts (splice variants), 132 orthologues and 7 paralogues. Broad expression in lymph node (RPKM 64.9), spleen (RPKM 59.9) and 22 other tissues.

Summary

This gene encodes a protein belonging to the GTP-binding superfamily and to the immuno-associated nucleotide (IAN) subfamily of nucleotide-binding proteins. The encoded protein of this gene may be negatively regulated by T-cell acute lymphocytic leukemia 1 (TAL1). In humans, the IAN subfamily genes are located in a cluster at 7q36.1. [provided by RefSeq, Jul 2008]

GIMAP4 Products (2)

mRNA Protein Name
NM_001363532.2 NP_001350461.1 GTPase IMAP family member 4 isoform 2
NM_018326.3 NP_060796.1 GTPase IMAP family member 4 isoform 1

Gene Ontology

  • Cellular Component
Cellular Component GO Annotation Evidence References Source
located in cytosol IDA
IDA: Inferred from direct assay
23454188 GOA
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

GIMAP4 Protein Structure

AIG1

AIG1: AIG1 family (31 - 238)

  • 0
  • 100
  • 200
  • 300
  • 329 a.a.
Protein Preferred Names Protein Names

GTPase IMAP family member 4

  • human immune associated nucleotide 1

Related Diseases

Diseases Alias
Retinitis Pigmentosa 19

  • RP19

  • Retinitis Pigmentosa-19

  • Retinitis Pigmentosa, Type 19
Behcet Syndrome

  • Behcet Disease

  • Behcet'S Syndrome

  • Behcet'S Disease

  • Behçet Disease

  • Bd

  • Adamantiades-Behcet Disease

  • Triple Symptom Complex

  • Behçet'S Disease

  • Behet'S Syndrome

  • Bd Syndrome

  • Behçet Syndrome

  • Behçet'S Syndrome

  • Behcet Triple Symptom Complex

  • Malignant Aphthosis

  • Old Silk Route Disease

  • Adamantiades-Behçet Disease
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS05424 GIMAP4 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Canis familiaris GIMAP4 VGNC VGNC:41217
Rattus norvegicus GIMAP4 RGD RGD:628765
Mus musculus GIMAP4 MGD MGI:1349656
Macaca mulatta GIMAP4 VGNC VGNC:72982
Others GIMAP4 NCBI