PPP3R2 - protein phosphatase 3 regulatory subunit B, beta Gene

Homo sapiens

Also known as PPP3RL

Gene ID: 5535 | Gene type: protein coding

About PPP3R2

Cytogenetic location: 9q31.1 Genomic coordinates (GRCh38): 9:101,591,604-101,594,969 (from NCBI)

This gene has 2 transcripts (splice variants), 32 orthologues and 8 paralogues.

Summary

Predicted to enable calcium ion binding activity and calcium-dependent protein serine/threonine Phosphatase regulator activity. Predicted to be involved in regulation of catalytic activity. Predicted to act upstream of or within penetration of zona pellucida. Predicted to be located in sperm mitochondrial sheath. Predicted to be part of calcineurin complex. [provided by Alliance of Genome Resources, Apr 2022]

PPP3R2 Products(1)

mRNA	Protein	Name
NM_147180.4	NP_671709.2	calcineurin subunit B type 2

PPP3R2 Protein Structure

EF-hand_7

0
100
173 a.a.

Protein Preferred Names

Protein Names

calcineurin subunit B type 2

CBLP

Related Diseases

Diseases

Alias

Cataract 3, Multiple Types

Cataract 3 Multiple Types	CTRCT3
Cca2	Cataract, Congenital, Cerulean Type, 2
Cataract 3, Multiple Types, With Or Without Microcornea	Cataract 3 Multiple Types With Or Without Microcornea
Congenital Cerulean Type Cataract 2	Congenital Cataract Blue Dot Type 2
Congenital Cataract Cerulean Type 2	Cspc
Sutural Cataract With Punctate And Cerulean Opacities

Diseases	Alias
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS11027	PPP3R2 Human Pre-designed siRNA Set A		/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Mus musculus	PPP3R2	MGD	MGI:107171
Rattus norvegicus	PPP3R2	RGD	RGD:69232

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