ASPDH - aspartate dehydrogenase domain containing Gene
Species: Homo sapiens
About ASPDH
This gene has 8 transcripts (splice variants) and 177 orthologues. Biased expression in liver (RPKM 17.1), kidney (RPKM 16.9) and 2 other tissues.
Summary
Predicted to enable NADP binding activity; aspartate dehydrogenase NAD activity; and aspartate dehydrogenase NADP activity. Predicted to be involved in NAD biosynthetic process. [provided by Alliance of Genome Resources, Apr 2022]
ASPDH Products (2)
| mRNA | Protein | Name |
|---|---|---|
| NM_001024656.3 | NP_001019827.2 | aspartate dehydrogenase domain-containing protein isoform 2 |
| NM_001114598.2 | NP_001108070.1 | aspartate dehydrogenase domain-containing protein isoform 1 |
ASPDH Protein Structure
NAD_binding_3: Homoserine dehydrogenase, NAD binding domain (13 - 123)
DUF108: Domain of unknown function DUF108 (170 - 266)
- 0
- 100
- 200
- 283 a.a.
| Protein Preferred Names | Protein Names | |
|---|---|---|
|
aspartate dehydrogenase domain-containing protein putative L-aspartate dehydrogenase |
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Related Diseases
| Diseases | Alias | |
|---|---|---|
| Cyclosporiasis |
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Orthologs Information
| Species | Symbol | Source | ID |
|---|---|---|---|
| Macaca mulatta | ASPDH | VGNC | VGNC:108470 |
| Rattus norvegicus | ASPDH | RGD | RGD:1310111 |
| Bos taurus | ASPDH | VGNC | VGNC:52180 |
| Canis familiaris | ASPDH | VGNC | VGNC:38185 |
| Felis catus | ASPDH | VGNC | VGNC:59974 |
| Mus musculus | ASPDH | MGD | MGI:1915602 |
| Others | ASPDH | NCBI |