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CAMK2N1 - calcium/calmodulin dependent protein kinase II inhibitor 1 Gene

Also Known as PRO1489

Species: Homo sapiens

Gene Type: protein coding

Gene ID: 55450

About CAMK2N1

Cytogenetic location: 1p36.12 Genomic coordinates (GRCh38): 1:20,482,391-20,486,210 (from NCBI)

This gene has 2 transcripts (splice variants), 183 orthologues and 1 paralogue. Broad expression in brain (RPKM 113.3), colon (RPKM 48.8) and 15 other tissues.

Summary

Enables calcium-dependent protein kinase inhibitor activity and protein kinase binding activity. Involved in several processes, including negative regulation of ERK1 and ERK2 cascade; negative regulation of cell population proliferation; and negative regulation of cellular protein metabolic process. Predicted to be located in synapse. Implicated in ovarian cancer; ovarian carcinoma; and prostate adenocarcinoma. Biomarker of hepatocellular carcinoma; oral squamous cell carcinoma; prostate cancer; and thyroid gland papillary carcinoma. [provided by Alliance of Genome Resources, Apr 2022]

CAMK2N1 Products (1)

mRNA	Protein	Name
NM_018584.6	NP_061054.2	calcium/calmodulin-dependent protein kinase II inhibitor 1

CAMK2N1 Protein Structure

CaM-KIIN

0
78 a.a.

Protein Preferred Names	Protein Names
calcium/calmodulin-dependent protein kinase II inhibitor 1	CaMKIINalpha

Related Diseases

Diseases	Alias
Mucinous Cystadenocarcinoma Of Pancreas	Pancreatic Mucinous Cystadenocarcinoma Mucinous Cystadenocarcinoma Of The Pancreas Pancreatic Colloid Cystadenocarcinoma
Oral Squamous Cell Carcinoma	Mouth Squamous Cell Carcinoma Squamous Cell Carcinoma Of Mouth
Ovarian Cancer	Ovarian Carcinoma Ovarian Neoplasm Malignant Tumour Of Ovary Cancer Of The Ovary Epithelial Ovarian Cancer Neoplasm Of Ovary Ovarian Neoplasms Ovarian Cancers Malignant Neoplasm Of Ovary Primary Malignant Neoplasm Of Ovary Ovarian Cancer, Somatic Malignant Ovarian Tumor Ovary Neoplasm Primary Ovarian Cancer Tumor Of The Ovary Malignant Neoplasm Of The Ovary Malignant Tumor Of The Ovary Ovarian Malignant Tumor OC Ovarian Carcinomas Cancer, Ovarian Cancer Of Ovary Ovary Cancer Ca Ovary
Prostate Cancer	Prostate Carcinoma Prostate Cancer, Familial Prostate Neoplasm Prostate Cancer, Somatic Prostate Cancer, Susceptibility To Prostatic Cancer Prostatic Neoplasms Hereditary Prostate Cancer Prostatic Neoplasm Cancer Of Prostate Carcinoma Of Prostate Familial Prostate Cancer Familial Prostate Carcinoma Malignant Tumor Of Prostate Malignant Neoplasm Of Prostate Prostate Cancer, Familial, Susceptibility To Malignant Tumor Of The Prostate Ngp - New Growth Of Prostate Tumor Of The Prostate Prostate Cancer, Hereditary Cancer Of The Prostate Malignant Neoplasm Of The Prostate Prostatic Carcinoma PC Prca Cancer, Prostate Malignant Prostatic Tumour Malignant Tumour Of Prostate Primary Prostate Cancer Primary Malignant Neoplasm Of Prostate Prostate Gland Cancer

Diseases	Alias
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS01862	CAMK2N1 Human Pre-designed siRNA Set A	Pre-designed Set	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Rattus norvegicus	CAMK2N1	RGD	RGD:708430
Mus musculus	CAMK2N1	MGD	MGI:1913509
Bos taurus	CAMK2N1	VGNC	VGNC:26723
Felis catus	CAMK2N1	VGNC	VGNC:80153
Macaca mulatta	CAMK2N1	VGNC	VGNC:106332