CAMK2N1 - calcium/calmodulin dependent protein kinase II inhibitor 1 Gene

Homo sapiens

Also known as PRO1489

Gene ID: 55450 | Gene type: protein coding

About CAMK2N1

Cytogenetic location: 1p36.12 Genomic coordinates (GRCh38): 1:20,482,391-20,486,210 (from NCBI)

This gene has 2 transcripts (splice variants), 183 orthologues and 1 paralogue. Broad expression in brain (RPKM 113.3), colon (RPKM 48.8) and 15 other tissues.

Summary

Enables calcium-dependent protein kinase inhibitor activity and protein kinase binding activity. Involved in several processes, including negative regulation of ERK1 and ERK2 cascade; negative regulation of cell population proliferation; and negative regulation of cellular protein metabolic process. Predicted to be located in synapse. Implicated in ovarian cancer; ovarian carcinoma; and prostate adenocarcinoma. Biomarker of hepatocellular carcinoma; oral squamous cell carcinoma; prostate cancer; and thyroid gland papillary carcinoma. [provided by Alliance of Genome Resources, Apr 2022]

CAMK2N1 Products(1)

mRNA	Protein	Name
NM_018584.6	NP_061054.2	calcium/calmodulin-dependent protein kinase II inhibitor 1

CAMK2N1 Protein Structure

CaM-KIIN

0
78 a.a.

Protein Preferred Names

Protein Names

calcium/calmodulin-dependent protein kinase II inhibitor 1

CaMKIINalpha

Related Diseases

Diseases

Alias

Mucinous Cystadenocarcinoma Of Pancreas

Pancreatic Mucinous Cystadenocarcinoma	Mucinous Cystadenocarcinoma Of The Pancreas
Pancreatic Colloid Cystadenocarcinoma

Oral Squamous Cell Carcinoma

Mouth Squamous Cell Carcinoma

Squamous Cell Carcinoma Of Mouth

Ovarian Cancer

Ovarian Carcinoma	Ovarian Neoplasm
Malignant Tumour Of Ovary	Cancer Of The Ovary
Epithelial Ovarian Cancer	Neoplasm Of Ovary
Ovarian Neoplasms	Ovarian Cancers
Malignant Neoplasm Of Ovary	Primary Malignant Neoplasm Of Ovary
Ovarian Cancer, Somatic	Malignant Ovarian Tumor
Ovary Neoplasm	Primary Ovarian Cancer
Tumor Of The Ovary	Malignant Neoplasm Of The Ovary
Malignant Tumor Of The Ovary	Ovarian Malignant Tumor
OC	Ovarian Carcinomas
Cancer, Ovarian	Cancer Of Ovary
Ovary Cancer	Ca Ovary

Prostate Cancer

Prostate Carcinoma	Prostate Cancer, Familial
Prostate Neoplasm	Prostate Cancer, Somatic
Prostate Cancer, Susceptibility To	Prostatic Cancer
Prostatic Neoplasms	Hereditary Prostate Cancer
Prostatic Neoplasm	Cancer Of Prostate
Carcinoma Of Prostate	Familial Prostate Cancer
Familial Prostate Carcinoma	Malignant Tumor Of Prostate
Malignant Neoplasm Of Prostate	Prostate Cancer, Familial, Susceptibility To
Malignant Tumor Of The Prostate	Ngp - New Growth Of Prostate
Tumor Of The Prostate	Prostate Cancer, Hereditary
Cancer Of The Prostate	Malignant Neoplasm Of The Prostate
Prostatic Carcinoma	PC
Prca	Cancer, Prostate
Malignant Prostatic Tumour	Malignant Tumour Of Prostate
Primary Prostate Cancer	Primary Malignant Neoplasm Of Prostate
Prostate Gland Cancer

Diseases	Alias
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS01862	CAMK2N1 Human Pre-designed siRNA Set A		/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Rattus norvegicus	CAMK2N1	RGD	RGD:708430
Mus musculus	CAMK2N1	MGD	MGI:1913509
Bos taurus	CAMK2N1	VGNC	VGNC:26723
Felis catus	CAMK2N1	VGNC	VGNC:80153
Macaca mulatta	CAMK2N1	VGNC	VGNC:106332

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